Nichtinfekti?se tubulointerstitielle Nephritis

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• 作者：Prof. Dr. Anke Schwarz (1)
  
• 关键词：Akute interstitielle Nephritis ; Chronische interstitielle Nephritis ; ?Chinese herbs nephropathy-/li> Analgetikanephropathie ; Balkan ; Nephropathie ; Acute interstitial nephritis ; Chronic interstitial nephritis ; Chinese herbs nephropathy ; Analgesic nephropathy ; Balkan nephropathy
• 刊名：Der Nephrologe
• 出版年：2010
• 出版时间：July 2010
• 年：2010
• 卷：5
• 期：4
• 页码：299-306
• 全文大小：487KB
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• 作者单位：Prof. Dr. Anke Schwarz (1)
  
  1. Abteilung Nephrologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland
  

文摘

Acute tubulo-interstitial nephritis is usually a reaction to infection or medication. The symptoms of the acute form may be lumbar pain, fever, and oligo-anuria, sometimes exanthema. However, symptoms may also be subacute or absent. If medication is continued in this setting, the nephritis may become chronic and irreversible. Chronic interstitial nephritis is often the end-stage of other renal diseases, in particular chronic infection, but also immunological diseases including chronic renal allograft rejection. Analgesic nephropathy due to the intake of mixed analgesics over many years has become rare, either due to socio-cultural changes or to changes in the range of medications on offer. The classic diagnostic sign of toxic nephropathy is papillary necrosis. Both Chinese herbs nephropathy and Balkan nephropathy are also toxic nephropathies caused by the Aristolochia plant, partly in the form of Chinese tea preparations and partly as a result of grain contamination due to plants growing in close proximity to one another. Toxic nephropathies are often associated with urothelial carcinoma.