Physical Activity is Associated with Better Neurocognitive and Everyday Functioning Among Older Adults with HIV Disease

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• 作者：Pariya L. Fazeli ; Maria J. Marquine ; Catherine Dufour ; Brook L. Henry…
• 关键词：Exercise ; Aging ; HIV/AIDS ; Cognition ; IADLs ; Physical therapy
• 刊名：AIDS and Behavior
• 出版年：2015
• 出版时间：August 2015
• 年：2015
• 卷：19
• 期：8
• 页码：1470-1477
• 全文大小：477 KB
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• 作者单位：Pariya L. Fazeli (1)
  Maria J. Marquine (1) (3)
  Catherine Dufour (1)
  Brook L. Henry (1)
  Jessica Montoya (4)
  Ben Gouaux (1)
  Raeanne C. Moore (1) (3)
  Scott L. Letendre (2)
  Steven Paul Woods (5)
  Igor Grant (1)
  Dilip V. Jeste (1) (3)
  David J. Moore (1) (6)
  The HNRP Group
  
  1. Department of Psychiatry, University of California San Diego, San Diego, CA, USA
  3. Stein Institute for Research on Aging, University of California San Diego, San Diego, CA, USA
  4. SDSU/UCSD Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA
  2. Department of Medicine, University of California San Diego, San Diego, CA, USA
  5. Department of Psychology, University of Houston, Houston, TX, USA
  6. HIV Neurobehavioral Research Program, University of California San Diego, 220 Dickinson Street, Suite B (8231), San Diego, CA, 92103, USA
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Public Health
  Health Psychology
  Infectious Diseases
  
• 出版者：Springer Netherlands
• ISSN：1573-3254

文摘

We examined the association between physical activity (PA), neurocognitive impairment (NCI), and instrumental activities of daily living (IADLs) among older HIV+?persons. One hundred older HIV+?adults completed the International Physical Activity Questionnaire, a neurocognitive battery, and IADL scale. Higher levels of moderate PA were associated with lower odds of NCI (p?=?0.01), even when covariates were modeled. The association between moderate PA and NCI was driven by executive function (p?=?0.04). Higher levels of moderate PA were also associated with lower odds of IADL Dependence (p?=?0.03), although this fell to a trend (p?=?0.08) when including covariates. Follow-up analysis showed those with both NCI and IADL Dependence had lower moderate PA than those with neither (p?=?0.03). While these cross-sectional findings suggest PA is associated with better neurocognitive and everyday functioning in older HIV+?adults, longitudinal studies utilizing objective PA methods are needed to evaluate directionality and mechanisms.