Anatomical liver segmentectomy 2 for combined hepatocellular carcinoma and cholangiocarcinoma with tumor thrombus in segment 2 portal branch

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• 作者：Hiromichi Ishii (1)
  Takuma Kobayashi (1)
  Michihiro Kudou (1)
  Masumi Nishimura (1)
  Atsushi Toma (1)
  Kenji Nakamura (1)
  Takeshi Mazaki (2)
  Tsuyoshi Itoh (1)
  
• 关键词：anatomical segmentectomy 2 ; portal vein tumor thrombus ; combined hepatocellular carcinoma and cholangiocarcinoma ; modified selective hepatic vascular exclusion
• 刊名：World Journal of Surgical Oncology
• 出版年：2012
• 出版时间：December 2012
• 年：2012
• 卷：10
• 期：1
• 全文大小：938KB
• 参考文献：1. Goodman ZD, Ishak KG, Langloss JM: Combined hepatocellular cholangiocarcinoma. A histologic and immunohistochemical study. / Cancer 1985, 55:124鈥?35. CrossRef
  2. Jarnagin WR, Weber S, Tickoo SK, Koea JB, Obiekwe S, Fong Y, DeMatteo RP, Blumgart LH, Klimstra D: Combined hepatocellular and cholangiocarcinoma: demographic, clinical, and prognostic factors. / Cancer 2002, 94:2040鈥?046. CrossRef
  3. Yano Y, Yamamoto J, Kosuge T, Sakamoto Y, Yamasaki S, Shimada K, Ojima H, Sakamoto M, Takayama T, Makuuchi M: Combined hepatocellular and cholangiocarcinoma: a clinicopathologic study of 26 resected cases. / Jpn J Clin Oncol 2003, 33:283鈥?87. CrossRef
  4. Liu CL, Fan ST, Lo CM, Ng IO, Lam CM, Poon RT, Wong J: Hepatic resection for combined hepatocellular and cholangiocarcinoma. / Arch Surg 2003, 138:86鈥?0. CrossRef
  5. Park H, Choi KH, Choi SB, Choi JW, Kim do Y, Ahn SH, Kim KS, Choi JS, Han KH, Chon CY, Park JY: Clinicopathological characteristics in combined hepatocellular-cholangiocarcinoma: a single center study in Korea. / Yonsei Med J 2011, 52:753鈥?60. CrossRef
  6. Lin DX, Zhang QY, Li X, Ye QY, Lin F, Li LL: An aggressive approach leads to improved survival in hepatocellular carcinoma patients with portal vein tumor thrombus. / J Cancer Res Clin Oncol 2011, 137:139鈥?49. CrossRef
  7. Minagawa M, Makuuchi M, Takayama T, Ohtomo K: Selection criteria for hepatectomy in patients with hepatocellular carcinoma and portal vein tumor thrombus. / Ann Surg 2001, 233:379鈥?84. CrossRef
  8. Liver Cancer Study Group of Japan: / The general rules for the clinical and pathological study of primary liver cancer. 2nd English edition. Tokyo: Kanehara Press; 2003.
  9. Makuuchi M, Mori T, Gunven P, Yamazaki S, Hasegawa H: Safety of hemihepatic vascular occlusion during resection of the liver. / Surg Gynecol Obstet 1987, 164:155鈥?58.
  10. Wittekind C, Fischer HP, Ponchon T: Combined hepatocellular and cholangiocarcinoma. In / World Health Organization classification of tumours of the digestive system. Edited by: Hamilton SR, Aaltonen LA. Lyon: IARC Press; 2000:181.
  11. Kim JH, Yoon HK, Ko GY, Gwon DI, Jang CS, Song HY, Shin JH, Sung KB: Nonresectable combined hepatocellular carcinoma and cholangiocarcinoma: analysis of the response and prognostic factors after transcatheter arterial chemoembolization. / Radiology 2010, 255:270鈥?77. CrossRef
  12. Sadamori H, Matsuda H, Shinoura S, Umeda Y, Yoshida R, Sato D, Utsumi H, Ohnishi H, Yagi T: Anatomical subsegmentectomy in the lateral segment for hepatocellular carcinoma. / Hepatogastroenterology 2009, 56:1511鈥?515.
  13. Radtke A, Sotiropoulos GC, Molmenti EP, Schroeder T, Peitgen HO, Frilling A, Broering DC, Broelsch CE, Malago' M: Computer-assisted surgery planning for complex liver resections: When is it helpful? A single-center experience over an 8-year period. / Ann Surg 2010, 252:876鈥?83. CrossRef
  14. Torzilli G, Makuuchi M: Ultrasound-guided finger compression in liver subsegmentectomy for hepatocellular carcinoma. / Surg Endosc 2004, 18:136鈥?39. CrossRef
  15. Kawasaki S, Makuuchi M, Harada H, Takayama T, Kosuge T: A new alternative hepatectomy method for resection of segment 3 and 4 of the liver. / Surg Gynecol Obstet 1992, 175:267鈥?69.
  16. Mutter D, Dallemagne B, Bailey Ch, Soler L, Marescaux J: 3D virtual reality and selective vascular control for laparoscopic left hepatic lobectomy. / Surg Endosc 2009, 23:432鈥?35. CrossRef
  17. Ueno S, Sakoda M, Kurahara H, Iino S, Minami K, Ando K, Mataki Y, Maemura K, Ishigami S, Takumi K, Fukukura Y, Natsugoe S: Preoperative segmentation of the liver, based on 3D CT images, facilitates laparoscopic anatomic hepatic resection for small nodular hepatocellular carcinoma in patients with cirrhosis. / Hepatogastroenterology 2010, 57:807鈥?12.
  18. Lau WY, Lai ECH, Lau SHY: Methods of vascular control technique during liver resection: a comprehensive review. / Hepatobiliary Pancreat Dis Int 2010, 9:473鈥?81.
  19. Fu SY, Lai EC, Li AJ, Pan ZY, Yang Y, Sun YM, Lau WY, Wu MC, Zhou WP: Liver resection with selective hepatic vascular exclusion: a cohort study. / Ann Surg 2009, 249:624鈥?27. CrossRef
  20. Zhou W, Li A, Pan Z, Fu S, Yang Y, Tang L, Hou Z, Wu M: Selective hepatic vascular exclusion and Pringle maneuver: a comparative study in liver resection. / Eur J Surg Oncol 2008, 34:49鈥?4. CrossRef
  
• 作者单位：Hiromichi Ishii (1)
  Takuma Kobayashi (1)
  Michihiro Kudou (1)
  Masumi Nishimura (1)
  Atsushi Toma (1)
  Kenji Nakamura (1)
  Takeshi Mazaki (2)
  Tsuyoshi Itoh (1)
  
  1. Division of Surgery, Kyoto Prefectural Yosanoumi Hospital, 481 Otokoyama, Yosano-cho, Yosa-gun, Kyoto, 629-2261, Japan
  2. Division of Pathology, Kyoto Prefectural Yosanoumi Hospital, 481 Otokoyama, Yosano-cho, Yosa-gun, Kyoto, 629-2261, Japan
  

文摘

Background Hepatic resection is the only effective treatment for combined hepatocellular carcinoma and cholangiocarcinoma. Case presentation A 52-year-old man was preoperatively diagnosed with hepatocellular carcinoma in segment 2 with tumor thrombus in the segment 2 portal branch. Anatomical liver segmentectomy 2, including separation of the hepatic arteries, portal veins, and bile duct, enabled us to remove the tumor and portal thrombus completely. Modified selective hepatic vascular exclusion, which combines extrahepatic control of the left and middle hepatic veins with occlusion of left hemihepatic inflow, was used to reduce blood loss. A pathological examination revealed combined hepatocellular carcinoma and cholangiocarcinoma with tumor thrombus in the segment 2 portal branch. No postoperative liver failure occurred, and remnant liver function was adequate. Conclusion The separation method of the hepatic arteries, portal veins, and bile duct is safe and feasible for a liver cancer patient with portal vein tumor thrombus. Modified selective hepatic vascular exclusion was useful to control bleeding during liver transection. Anatomical liver segmentectomy 2 using these procedures should be considered for a patient with a liver tumor located at segment 2 arising from a damaged liver.