Effect of depth of general anesthesia on the threshold of electrically evoked compound action potential in cochlear implantation

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• 作者：Ali Eftekharian ; Maryam Amizadeh…
• 关键词：Cochlear implant ; General anesthesia ; Depth of anesthesia ; Electrically evoked compound action potential ; Auditory evoked compound action potential
• 刊名：European Archives of Oto-Rhino-Laryngology
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：272
• 期：10
• 页码：2697-2701
• 全文大小：336 KB
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• 作者单位：Ali Eftekharian (1)
  Maryam Amizadeh (1)
  Kamran Mottaghi (2)
  Farhad Safari (2)
  Mozhgan Hosseinerezai Mahani (1)
  Leila Azadeh Ranjbar (3)
  Ali Abdi (3)
  Nooshin Mokari (3)
  
  1. Department of Otorhinolaryngology, Loghman Hospital, Shahid-Beheshti University of medical sciences, Kamali Ave. Kargar, 13336-31151, Tehran, Iran
  2. Department of Anesthesia, Shahid-Beheshti University of medical sciences, Tehran, Iran
  3. Department of Audiology, Shahid-Beheshti University of medical sciences, Tehran, Iran
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Otorhinolaryngology
  Neurosurgery
  Head and Neck Surgery
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1434-4726

文摘

The purpose of the present study was to evaluate effect of depth of general anesthesia on the threshold of electrically evoked compound action potential in cochlear implantation. A prospective clinical study in a single-subject design was conducted in the cochlear implant center of a tertiary care University-based hospital. Sixty-one cochlear-implanted children with bilateral, severe to profound sensory neural hearing loss were enrolled in the study. During the operation electrically evoked compound action potentials (e-ECAP) were measured in two phase of general anesthesia; in deep and in light anesthesia. Thresholds of e-ECAP in these two phases of anesthesia were compared. Thirty-one children received HiRes90k1j prosthesis and 30 children received CI24RE prosthesis. Thresholds difference of electrically evoked compound action potential between light and deep anesthesia in all tested electrodes in either group were statistically significant (P < 0.001). Non-measurable e-ECAP in some electrodes at deep anesthesia was measurable in light phase of anesthesia. Depth of anesthesia can have significant influence on e-ECAP threshold and it is important to reduce the depth of anesthesia to achieve better results. Keywords Cochlear implant General anesthesia Depth of anesthesia Electrically evoked compound action potential Auditory evoked compound action potential