Suicide and suicide attempts in people with severe mental disorders in Butajira, Ethiopia: 10?year follow-up of a population-based cohort

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• 作者：Teshome Shibre ; Charlotte Hanlon ; Girmay Medhin ; Atalay Alem…
• 关键词：Suicide ; Schizophrenia ; Major depression ; Bipolar I disorder ; Developing countries ; sub ; Saharan Africa ; Ethiopia
• 刊名：BMC Psychiatry
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：14
• 期：1
• 全文大小：295 KB
• 参考文献：The Global Burden of Disease: 2004 Update. World Health Organization, Geneva
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• 刊物主题：Psychiatry; Psychotherapy;
• 出版者：BioMed Central
• ISSN：1471-244X

文摘

Background People with severe mental disorders (SMD) are at higher risk of suicide. However, research into suicide attempts and completed suicide in people with SMD in low- and middle-income countries is mostly limited to patients attending psychiatric facilities where selection bias is likely to be high. Methods A population-based cohort of 919 people with SMD from rural Ethiopia (who received standardized clinician diagnoses of schizophrenia (n--58) major depressive disorder (n--16) and bipolar I disorder (n--45)) were followed up annually for an average of 10?years. The Longitudinal Interval Follow-up Evaluation chart was administered by psychiatrists and used to evaluate systematically suicidal behavior and risk factors, which may be amenable to intervention. Results Over the follow-up period, the cumulative risk of suicide attempt was 26.3% for major depression, 23.8% for bipolar I disorder and 13.1% for schizophrenia, (p--.001). The overall incidence of completed suicide was 200.2/100,000 person-years (CI--20.6, 312.5). Hanging was the most frequent method used (71.5%) for both attempters and completers. Most people who completed suicide were successful on the first attempt (84.2%), but the case-fatality rate for suicide attempt was 9.7%. In the adjusted logistic regression model, being currently married (Adjusted OR) =2.17, 95% CI--.21, 3.91), and having a diagnosis of bipolar I disorder (Adjusted OR--.59, 95% CI--.57, 4.26) or major depression (Adjusted OR--.71, 95% CI--.60, 4.58) were associated significantly with increased risk of suicide attempts. Conclusion In this sample of people with SMD from a rural setting, the rate of suicide was high. Initiatives to integrate mental health service into primary care need to focus on limiting access to suicide methods in people with SMD in addition to expanding access to mental health care.