Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease

详细信息    查看全文

• 作者：Charbel Moussa ; Michaeline Hebron ; Xu Huang ; Jaeil Ahn…
• 关键词：Resveratrol ; Matrix metalloproteinase ; (MMP) ; 9 ; Alzheimer ; Interleukin ; 4 ; Macrophage ; derived chemokine (MDC)
• 刊名：Journal of Neuroinflammation
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：14
• 期：1
• 全文大小：1108KB
• 刊物主题：Neurosciences; Neurology; Neurobiology; Immunology;
• 出版者：BioMed Central
• ISSN：1742-2094
• 卷排序：14

文摘

BackgroundTreatment of mild-moderate Alzheimer’s disease (AD) subjects (N = 119) for 52 weeks with the SIRT1 activator resveratrol (up to 1 g by mouth twice daily) attenuates progressive declines in CSF Aβ40 levels and activities of daily living (ADL) scores.