A Systematic Review of Current Understanding and Management of Mastalgia

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• 作者：Kamal Kataria ; Anita Dhar ; Anurag Srivastava ; Sandeep Kumar…
• 关键词：Mastalgia ; Cyclical mastalgia ; Noncyclical mastalgia ; Centchroman ; Danazol ; Diclofenac gel
• 刊名：Indian Journal of Surgery
• 出版年：2014
• 出版时间：June 2014
• 年：2014
• 卷：76
• 期：3
• 页码：217-222
• 全文大小：694 KB
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• 作者单位：Kamal Kataria (1)
  Anita Dhar (1)
  Anurag Srivastava (1)
  Sandeep Kumar (2)
  Amit Goyal (3)
  
  1. Department of Surgical Disciplines, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India
  2. Department of Surgical Disciplines, All India Institute of Medical Sciences, Bhopal, India
  3. Derbyshire Breast Unit, Derbyshire, UK
  
• ISSN：0973-9793

文摘

Breast pain or mastalgia is the common symptom in the breast. The two most common concerns of patients presenting with mastalgia are: the fear that breast pain is a symptom of breast cancer and the presence of severe pain that affects a woman’s quality of life. Breast pain requires thorough assessment and should be investigated in the same manner as any other breast symptom. We conducted a systematic review of treatment for breast pain. We searched various reviews, randomized controlled trial, and observational studies over Pubmed and Medline via internet. Searches were carried out on MEDLINE (1950–present), EMBASE (1980–present), and CINAHL (1981–present) using the NHS Evidence Healthcare Databases Advanced Search interface. A further search was also carried out on Cochrane Database of Systematic Reviews (issue 12 of 12, Dec 2011) and Central Register of Controlled Trials (issue 4 of 4, Oct 2011). If no abnormality is found in the breast on assessment, then a combination of reassurance, breast support brassiere, and topical NSAID gel massage are usually effective. Antiestrogen (centchroman/tamoxifen) therapy for 3 to 6?months is the second-line treatment of choice. Danazol may be used in resistant cases. Gamma-linolenic acid or evening primrose oil though commonly prescribed is not effective.