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Olfaction deterioration in cognitive disorders in the elderly
- 作者:Giancarlo Ottaviano ; Giuliana Frasson…
- 关键词:Cognitive disorders ; Alzheimer’s disease ; Parkinson’s disease ; Elderly ; UPSIT ; Sniffin’ Sticks
- 刊名:Aging Clinical and Experimental Research
- 出版年:2016
- 出版时间:February 2016
- 年:2016
- 卷:28
- 期:1
- 页码:37-45
- 全文大小:426 KB
- 参考文献:1.Hummel T, Landis BN, Huttenbrink KB (2011) Smell and taste disorders. GMS Curr Top Otorhinolaryngol Head Neck Surg 10:Doc04. doi:10.3205/cto000077 PubMed PubMedCentral
2.Stevenson RJ (2010) An initial evaluation of the functions of human olfaction. Chem Senses 35:3–20CrossRef PubMed 3.Ackerl K, Atzmueller M, Grammer K (2002) The scent of fear. Neuro Endocrinol Lett 23:79–84PubMed 4.Ottaviano G, Zuccarello D, Frasson G et al (2013) Olfactory sensitivity and sexual desire in young adult and elderly men: an introductory investigation. Am J Rhinol Allergy 27:157–161CrossRef PubMed 5.Sorokowska A, Sorokowski P, Szmajke A (2012) Does personality smell? Accuracy of personality assessments based on body odour. Eu J Pers 26:496–503CrossRef 6.Buck L, Axel R (1991) A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65:175–187CrossRef PubMed 7.Sorokowska A, Schriever VA, Gudziol V et al (2014) Changes of olfactory abilities in relation to age: odor identification in more than 1400 people aged 4 to 80 years. Eur Arch Otorhinolaryngol. doi:10.1007/s00405-014-3263-4 PubMed PubMedCentral 8.Doty RL, Shaman P, Applebaum SL et al (1984) Smell identification ability: changes with age. Science 226:1441–1443CrossRef PubMed 9.Nyenhuis SM, Mathur SK (2013) Rhinitis in older adults. Curr Allergy Asthma Rep 13:171–177CrossRef PubMed PubMedCentral 10.Rahayel S, Frasnelli J, Joubert S (2012) The effect of Alzheimer’s disease and Parkinson’s disease on olfaction: a meta-analysis. Behav Brain Res 231:60–74CrossRef PubMed 11.Wilson RS, Arnold SE, Schneider JA et al (2009) Olfactory impairment in pre-symptomatic Alzheimer’s disease. Ann NY Acad Sci 1170:730–735CrossRef PubMed PubMedCentral 12.Doty RL (2012) Olfaction in Parkinson’s disease and related disorders. Neurobiol Dis 46:527–552CrossRef PubMed PubMedCentral 13.Hummel T, Kobal G, Gudziol H et al (2007) Normative data for the “Sniffin’ Sticks” including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3000 subjects. Eur Arch Otorhinolaryngol 264:237–243CrossRef PubMed 14.Sohrabi HR, Bates KA, Weinborn MG et al (2012) Olfactory discrimination predicts cognitive decline among community-dwelling older adults. Transl Psychiatry. doi:10.1038/tp.2012.43 15.Murphy C, Morgan CD, Geisler MW et al (2000) Olfactory event-related potentials and aging: normative data. Int J Psychophysiol 36:133–145CrossRef PubMed 16.Rawson NE (2006) Olfactory loss in aging. Sci Aging Knowledge Environ 5:pe6 17.Mobley AS, Rodriguez-Gil DJ, Imamura F et al (2014) Aging in the olfactory system. Trends Neurosci 37:77–84CrossRef PubMed PubMedCentral 18.Kern RC (2000) Chronic sinusitis and anosmia: pathologic changes in the olfactory mucosa. Laryngoscope 110:1071–1077CrossRef PubMed 19.Dulay M, Gesteland R, Shear P et al (2008) Assessment of the influence of cognition and cognitive processing speed on three tests of olfaction. J Clin Exp Neuropsychol 30:327–337CrossRef PubMed 20.Larsson M, Nilsson LG, Olofsson JK et al (2004) Demographic and cognitive predictors of cued odor identification: evidence from a population-based study. Chem Senses 29:547–554CrossRef PubMed 21.Serby M, Larson P, Kalkstein D (1991) The nature and course of olfactory deficits in Alzheimer’s disease. Am J Psychiatry 148:357–360CrossRef PubMed 22.Vyhnalek M, Magerova H, Andel R et al (2015) Olfactory identification in amnestic and non-amnestic mild cognitive impairment and its neuropsychological correlates. Neurol Sci 349:179–184CrossRef 23.Hedner M, Larsson M, Arnold N et al (2010) Cognitive factors in odor detection, odor discrimination, and odor identification tasks. J Clin Exp Neuropsychol 32:1062–1067CrossRef PubMed 24.Koss E, Weiffenbach JM, Haxby JV et al (1988) Olfactory detection and identification performance are dissociated in early Alzheimer’s disease. Neurology 38:1228–1232CrossRef PubMed 25.Potter H, Butters N (1980) An assessment of olfactory deficits in patients with damage to prefrontal cortex. Neuropsychologia 18:621–628CrossRef PubMed 26.Wilson DA, Sullivan RM (2011) Cortical processing of odor objects. Neuron 72:506–519CrossRef PubMed PubMedCentral 27.Hummel T, Kobal G (2002) Olfactory event-related potentials. In: Simon SA, Nicoleis MAL (eds) Methods in chemosensory research. CRC Press, London, pp 431–453 28.Welge-Lussen A (2009) Ageing, neurodegeneration, and olfactory and gustatory loss. B-ENT 5(Suppl 13):129–132PubMed 29.Kovàcs T (2004) Mechanisms of olfactory dysfunction in aging and neurodegenerative disorders. Ageing Res Rev 2004(3):215–232CrossRef 30.Hawkes CH, Shephard BC, Daniel SE (1999) Is Parkinson’s disease a primary olfactory disorder? QJM 92:473–480CrossRef PubMed 31.Sommer U, Hummel T, Cormann K et al (2004) Detection of presymptomatic Parkinson’s disease: combining smell tests, transcranial sonography, and SPECT. Mov Disord 19:1196–1202CrossRef PubMed 32.Bostantjopoulou S, Katsarou Z, Karakasis C et al (2013) Evaluation of non-motor symptoms in Parkinson’s disease: an underestimated necessity. Hippokratia 17:214–219PubMed PubMedCentral 33.Spillantini MG, Schmidt ML, Lee VM et al (1997) Alpha-synuclein in Lewy bodies. Nature 388:839–840CrossRef PubMed 34.Stroop WG (1995) Viruses and the olfactory system. In: Doty RL (ed) Handbook of olfaction and gustation. Marcel Dekker INC, New York, pp 367–393 35.Malec-Litwinowicz M, Rudzińska M, Szubiga M et al (2014) Cognitive impairment in carriers of glucocerebrosidase gene mutation in Parkinson disease patients. Neurol Neurochir Pol 48:258–261PubMed 36.Haehner A, Hummel T, Hummel C et al (2007) Olfactory loss may be a first sign of idiopathic Parkinson’s disease. Mov Disord 22:839–842CrossRef PubMed 37.Haehner A, Boesveldt S, Berendse HW et al (2009) Prevalence of smell loss in Parkinson’s disease-a multicenter study. Parkinsonism Relat Disord 15:490–494CrossRef PubMed 38.Doty RL, Deems DA, Stellar S (1988) Olfactory dysfunction in parkinsonism: a general deficit unrelated to neurologic signs, disease stage, or disease duration. Neurology 38:1237–1244CrossRef PubMed 39.Bohnen NI, Gedela S, Kuwabara H et al (2007) Selective hyposmia and nigrostriatal dopaminergic denervation in Parkinson’s disease. J Neurol 254:84–90CrossRef PubMed 40.Rezaie P, Cairns NJ, Chadwick A et al (1996) Lewy bodies are located preferentially in limbic areas in diffuse Lewy body disease. Neurosci Lett 212:111–114CrossRef PubMed 41.Braak H, Braak E, Yilmazer D et al (1994) Amygdala pathology in Parkinson’s disease. Acta Neuropathol 88:450–493CrossRef 42.Pearce RKB, Hawkes CH, Daniel SE (1995) The anterior olfactory nucleus in Parkinson’s disease. Mov Disord 10:283–287CrossRef PubMed 43.Bohnen NI, Muller ML, Kotagal V et al (2010) Olfactory dysfunction, central cholinergic integrity and cognitive impairment in Parkinson’s disease. Brain 133:1747–1754CrossRef PubMed PubMedCentral 44.Sun GH, Raji CA, Maceachern MP et al (2012) Olfactory identification testing as a predictor of the development of Alzheimer’s dementia: a systematic review. Laryngoscope 122:1455–1462CrossRef PubMed 45.Merril CS (2013) Is sporadic Alzheimer’s disease associated with diphtheria toxin? J Alzheimers Dis 34:595–600PubMed 46.Itzhaki RF, Wozniak MA, Appelt DM et al (2014) Infiltration of the brain by pathogens causes Alzheimer’s disease. Neurobiol Aging 25:619–627 Review CrossRef 47.Murphy C, Bacon AW, Bondi MW et al (1998) Apolipoprotein E status is associated with odor identification deficits in nondemented older persons. Ann N Y Acad Sci 855:744–750CrossRef PubMed 48.Graves AB, Bowen JD, Rajaram L et al (1999) Impaired olfaction as a marker for cognitive decline: interaction with apolipoprotein E epsilon4 status. Neurology 53:1480–1487CrossRef PubMed 49.D’introno A, Solfrizzi V, Colacicco AM et al (2006) Current knowledge of chromosome 12 susceptibility genes for late-onset Alzheimer’s disease. Neurobiol Aging 27:1537–1553CrossRef PubMed 50.Roberts E (1986) Alzheimer’s disease may begin in the nose and may be caused by aluminosilicates. Neurobiol Aging 7:561–567CrossRef PubMed 51.Talamo BR, Rudel R, Kosik KS et al (1989) Pathological changes in olfactory neurons in patients with Alzheimer’s disease. Nature 337:736–739CrossRef PubMed 52.Hock C, Golombowski S, Müller-Spahn F et al (1998) Histological markers in nasal mucosa of patients with Alzheimer’s disease. Eur Neurol 40:31–36CrossRef PubMed 53.Kovács T, Cairn NJ, Lantos PL (1999) Amyloid deposition and neurofibrillary tangle formation in the olfactory bulb in ageing and Alzheimer’s disease. Neuropathol Appl Neurobiol 25:481–491CrossRef PubMed 54.Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239–259CrossRef PubMed 55.Kovács T, Cairns NJ, Lantos PL (2001) Olfactory centres in Alzheimer’s disease: olfactory bulb is involved in early Braak’s stages. NeuroReport 12:285–288CrossRef PubMed 56.Kovacs I, Torok I, Zombori J et al (1998) Cholinergic structures and neuropathologic alterations in the olfactory bulb of Alzheimer’s disease brain samples. Brain Res 789:167–170CrossRef PubMed 57.Doty RL, Shaman P, Dann M (1994) Development of the University of Pennsylvania Smell Identification Test: a standardized microencapsulated test of olfactory function. Physiol Behav 32:489–502CrossRef 58.Hummel T, Sekinger B, Wolf SR et al (1997) Sniffin’ sticks’: olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold. Chem Senses 22:39–52CrossRef PubMed 59.Haehner A, Hummel T, Reichmann H (2011) Olfactory loss in Parkinson’s disease. Parkinsons Dis. doi:10.4061/2011/450939 PubMed PubMedCentral 60.Richardson JT, Zucco GM (1989) Cognition and olfaction: a review. Psychol Bull 105:352–360CrossRef PubMed 61.Doty RL, Marcus A, Lee WW (1996) Development of the 12-Item Cross-Cultural Smell Identification Test. Laryngoscope 106:353–356CrossRef PubMed 62.Jiang RS, Su MC, Liang KL et al (2010) A pilot study of a traditional Chinese version of the University of Pennsylvania Smell Identification Test for application in Taiwan. Am J Rhinol Allergy 24:45–50CrossRef PubMed 63.Silveira-Moriyama L, Azevedo AM et al (2010) Applying a new version of the Brazilian-Portuguese UPSIT smell test in Brazil. Arq Neuropsiquiatr 68:700–705CrossRef PubMed 64.Kobal G, Hummel T, Sekinger B et al (1996) “Sniffin’ Sticks”: screening of olfactory performace. Rhinology 34:222–226PubMed 65.Hummel T, Konnerth CG, Rosenheim K et al (2001) Screening of olfactory function with a four-minute odor identification test: reliability, normative data, and investigations in patients with olfactory loss. Ann Otol Rhinol Laryngol 110:976–981CrossRef PubMed 66.Haehner A, Mayer AM, Landis BN et al. (2009) High test-retest reliability of the extended version of the “Sniffin’ Sticks” test. Chem Senses 34:705–711CrossRef PubMed 67.Sorokowska A, Albrecht E, Haehner A et al (2015) Extended version of the “Sniffin’ Sticks” identification test: test-retest reliability and validity. J Neurosci Methods 243:111–114CrossRef PubMed 68.Kobal G (2003) Electrophysiological measurement of olfactory function. In: Doty RL (ed) Handbook of Olfaction and Gustation. Marcel Dekker INC, New York, pp 229–249 69.Rombaux P, Duprez T, Hummel T (2009) Olfactory bulb volume in the clinical assessment of olfactory dysfunction. Rhinology 47:3–9PubMed 70.Wang J, You H, Liu JF et al (2011) Association of olfactory bulb volume and olfactory sulcus depth with olfactory function in patients with Parkinson disease. AJNR Am J Neuroradiol 32:677–681CrossRef PubMed 71.Ottaviano G, Cantone E, D’Errico A et al. (2015) Sniffin’ Sticks and olfactory system imaging in patients with Kallmann syndrome. Int Forum Allergy Rhinol. doi:10.1002/alr.21550 PubMed 72.Baba T, Takeda A, Kikuchi A et al (2011) Association of olfactory dysfunction and brain. Metabolism in Parkinson’s disease. Mov Disord 26:621–628CrossRef PubMed 73.Berendse HW, Ponsen MM (2009) Diagnosing premotor Parkinson’s disease using a two-step approach combining olfactory testing and DAT SPECT imaging. Parkinsonism Relat Disord 15(Suppl. 3):S26–S30CrossRef PubMed 74.Deeb J, Shah M, Muhammed N et al (2010) A basic smell test is as sensitive as a dopamine transporter scan: comparison of olfaction, taste and DaTSCAN in the diagnosis of Parkinson’s disease. QJM 103:941–952CrossRef PubMed 75.Mesholam RI, Moberg PJ, Mahr RN et al (1998) Olfaction in neurodegenerative disease. A meta-analysis of olfactory functioning in Alzheimer’s and Parkinson’s diseases. Arch Neurol 55:84–90CrossRef PubMed 76.Herting B, Schulze S, Reichmann H et al (2008) A longitudinal study of olfactory function in patients with idiopathic Parkinson’s disease. J Neurol 255:367–370CrossRef PubMed 77.Wong KK, Muller ML, Kuwabara H et al (2010) Olfactory loss and nigrostriatal dopaminergic denervation in the elderly. Neurosci Lett 484:163–167CrossRef PubMed 78.Wang J, Eslinger PJ, Doty RL et al (2010) Olfactory deficit detected by fMRI in early Alzheimer’s disease. Brain Res 1357:184–194CrossRef PubMed PubMedCentral 79.Babizhayev MA, DeyevAI Yegorov YE (2011) Olfactory dysfunction and cognitive impairment in age-related neurodegeneration: prevalence related to patient selection, diagnostic criteria and therapeutic treatment of aged clients receiving clinical neurology and community-based care. Curr Clin Pharmacol 6:236–259CrossRef PubMed 80.Koivisto H, Grimm MO, Rothhaar TL et al (2014) Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer’s disease independent of brain amyloid deposition. J Nutr Biochem 25:157–169CrossRef PubMed 81.Bernal-Mondragón C, Rivas-Arancibia S, Kendrick KM et al (2013) Estradiol prevents olfactory dysfunction induced by A-β 25-35 injection in hippocampus. BMC Neurosci 14:104CrossRef PubMed PubMedCentral 82.Haehner A, Tosch C, Wolz M et al (2013) Olfactory training in patients with Parkinson’s disease. PLoS ONE 8:e61680CrossRef PubMed PubMedCentral 83.Knudsen K, Flensborg Damholdt M, Mouridsen K et al. (2015) Olfactory function in Parkinson’s disease—effects of training. Acta Neurol Scand (Epub) 84.Cain WS, Gent JF, Goodspeed RB et al (1988) Evaluation of olfactory dysfunction in the Connecticut Chemosensory Clinical Research Center. Laryngoscope 98:83–88CrossRef PubMed 85.Takagi SF (1989) Standardized olfactometries in Japan–a review over 10 years. Chem Senses 14:25–46CrossRef 86.Liu HC, Wang SJ, Lin KP et al (1995) Performance on a smell screening test (the MODSIT): a study of 510 predominantly illiterate Chinese subjects. Physiol Behav 58:1251–1255CrossRef PubMed 87.Nordin S, Bramerson A, Liden E et al (1998) The Scandinavian odor-identification test: development, reliability, validity and normative data. Acta Otolaryngol 118:226–234CrossRef PubMed 88.Simmen D, Briner HR, Hess K (1999) Screening test des Geruchssinnes mit Riechdiskette. Laryngorhinootologie 78:125–130CrossRef PubMed 89.Kobal G, Palisch K, Wolf SR et al (2001) A threshold-like measure for the assessment of olfactory sensitivity: the “random” procedure. Eur Arch Otorhinolaryngol 258:168–172CrossRef PubMed 90.Kurtz DB, White TL, Sheehe PR et al (2001) Odorant confusion matrix: the influence of patient history on patterns of odorant identification and misidentification in hyposmia. Physiol Behav 72:595–602CrossRef PubMed 91.Kobayashi M, Saito S, Kobayakawa T et al (2006) Cross-cultural comparison of data using the odor stick identification test for Japanese (OSIT-J). Chem Senses 31:335–342CrossRef PubMed 92.Cardesín A, Alobid I, Benítez P et al (2006) Barcelona Smell Test—24 (BAST-24): validation and smell characteristics in the healthy Spanish population. Rhinology 44:83–89PubMed 93.Krantz EM, Schubert CR, Dalton DS et al (2009) Test-retest reliability of the San Diego odor identification test and comparison with the brief smell identification test. Chem Senses 34:435–440CrossRef PubMed PubMedCentral
- 作者单位:Giancarlo Ottaviano (1)
Giuliana Frasson (1) Ennio Nardello (1) Alessandro Martini (1)
1. Department of Neurosciences, Otolaryngology Section, University of Padova, Via Giustiniani 2, 35100, Padua, Italy
- 刊物主题:Geriatrics/Gerontology;
- 出版者:Springer International Publishing
- ISSN:1720-8319
文摘
Background Parkinson’s and Alzheimer’s diseases are widespread neurodegenerative pathologies. Parkinson’s disease affects about 1 % of the population over the age of 65 years, while Alzheimer is considered the most common cause of dementia, with an annual incidence of 1 % in persons aged 65 years. It has been demonstrated that both these neurodegenerative diseases are associated with smell dysfunction.
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