CRIT-LINE: a noninvasive tool to monitor hemoglobin levels in pediatric hemodialysis patients

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• 作者：Rouba Garro ; Scott Sutherland ; Liz Bayes ; Steven Alexander…
• 关键词：CRIT ; LINE ; Anemia ; Children ; Hemodialysis ; Hemoglobin
• 刊名：Pediatric Nephrology
• 出版年：2015
• 出版时间：June 2015
• 年：2015
• 卷：30
• 期：6
• 页码：991-998
• 全文大小：656 KB
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• 作者单位：Rouba Garro (1)
  Scott Sutherland (2)
  Liz Bayes (2) (3)
  Steven Alexander (2)
  Cynthia Wong (2)
  
  1. Department of Pediatrics, Division of Nephrology, Emory University, 2015 Uppergate Drive NE, Atlanta, GA, 30322, USA
  2. Department of Pediatrics, Division of Nephrology, Stanford University, Stanford, CA, USA
  3. Department of Pediatrics, University of Miami, Miami, FL, USA
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Pediatrics
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-198X

文摘

Background The national average for achieving the KDOQI-recommended hemoglobin (Hgb) target level of 11-2?g/dL is low with the current anemia management protocol of measuring Hgb levels every 2-?weeks to guide intervention. The objective of this study was to correlate initial Hgb readings from the CRIT-LINE monitor with actual serum Hgb levels in pediatric patients on hemodialysis (HD). Methods Data were collected from pediatric HD patients who had Hgb tests ordered for routine and/or clinical reasons. Hgb concentrations were read with the CRIT–LINE after 0.5 or 1?L of blood had been processed by HD in patients with a body weight of ?0 or >20?kg, respectively. Ultrafiltration was kept at a minimum until the CRIT-LINE Hgb was read. Results In total, 217 Hgb readings from 23 HD patients were analyzed. Results showed a statistically significant correlation between CRIT-LINE readings and laboratory Hgb measurements (r--.94, p-lt;-.0001) using Pearson correlation coefficients for well-distributed data. The mean Hgb levels measured by CRIT-LINE and the laboratory were 11.12?±-.63 and 11.31?±-.69?g/dL, respectively. Conclusions The CRIT-LINE monitor is an accurate instrument for monitoring Hgb levels in HD patients. Further studies will be needed to evaluate whether using CRIT-LINE Hgb levels to guide anemia management will improve the percentage of children with Hgb levels within target.