Neuroretinitis: a rare feature of tubulointerstitial nephritis and uveitis syndrome

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• 作者：Sana Khochtali (1) (4)
  Olfa Harzallah (2) (4)
  Rym Hadhri (3) (4)
  Cyrine Hamdi (1) (4)
  Sonia Zaouali (1) (4)
  Moncef Khairallah (1) (4)
  
• 关键词：Anterior uveitis ; Neuroretinitis ; Optic disc edema ; Serous retinal detachment ; Tubulointerstitial nephritis
• 刊名：International Ophthalmology
• 出版年：2014
• 出版时间：June 2014
• 年：2014
• 卷：34
• 期：3
• 页码：629-633
• 全文大小：
• 参考文献：1. Mandeville JTH, Levinson RD, Holland GN (2001) The tubulointerstitial nephritis and uveitis syndrome. Surv Ophthalmol 46:195-08 CrossRef
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• 作者单位：Sana Khochtali (1) (4)
  Olfa Harzallah (2) (4)
  Rym Hadhri (3) (4)
  Cyrine Hamdi (1) (4)
  Sonia Zaouali (1) (4)
  Moncef Khairallah (1) (4)
  
  1. Department of Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
  4. Faculty of Medicine, University of Monastir, Monastir, Tunisia
  2. Department of Internal Medicine, Fattouma Bourguiba University Hospital, Monastir, Tunisia
  3. Department of Pathology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
  
• ISSN：1573-2630

文摘

A 17-year-old female presented to our hospital with fatigue, arthralgia and fever associated with non-granulomatous anterior uveitis in the left eye. Blood tests revealed renal failure and a renal biopsy showed acute tubulointerstitial nephritis. Findings were consistent with tubulointerstitial nephritis and uveitis (TINU) syndrome. The patient received systemic corticosteroids for 2?months as well as dexamethasone and mydriatic drops. Bilateral non-granulomatous anterior uveitis occurred 10?days after prednisone discontinuation, and was treated with topical steroids; however, uveitis recurred several weeks later. Bilateral anterior chamber inflammation was associated with neuroretinitis in the right eye. Extensive posterior synechiae precluded fundus examination of the left eye. The posterior segment manifestations responded to systemic prednisone, which was slowly tapered. The final visual outcome was favorable. TINU syndrome may rarely manifest with neuroretinitis.