The golgin coiled-coil proteins capture different types of transport carriers via distinct N-terminal motifs

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• 作者：Mie Wong ; Alison K. Gillingham ; Sean Munro
• 关键词：Vesicle tethering ; Golgin ; Golgi ; Coiled ; coil ; Endosome ; to ; Golgi traffic ; Intra ; Golgi traffic
• 刊名：BMC Biology
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：15
• 期：1
• 全文大小：6822KB
• 刊物主题：Life Sciences, general;
• 出版者：BioMed Central
• ISSN：1741-7007
• 卷排序：15

文摘

BackgroundThe internal organization of cells depends on mechanisms to ensure that transport carriers, such as vesicles, fuse only with the correct destination organelle. Several types of proteins have been proposed to confer specificity to this process, and we have recently shown that a set of coiled-coil proteins on the Golgi, called golgins, are able to capture specific classes of carriers when relocated to an ectopic location.