Sequential treatment with aurora B inhibitors enhances cisplatin-mediated apoptosis via c-Myc
详细信息    查看全文
  • 作者:Yaxi Ma (2)
    Handi Cao (1)
    Siyue Lou (1)
    Xuejing Shao (1)
    Wen Lv (3)
    Xiaotian Qi (1)
    Yujia Liu (1)
    Meidan Ying (1)
    Qiaojun He (1)
    Xiaochun Yang (1)

    2. Department of Gynecology
    ; The Second Affiliated Hospital ; School of Medicine ; Zhejiang University ; Hangzhou ; 310009 ; China
    1. Institute of Pharmacology and Toxicology
    ; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research ; College of Pharmaceutical Sciences ; Zhejiang University ; Hangzhou ; 310058 ; China
    3. Tongde Hospital of Zhejiang Province
    ; Hangzhou ; 310009 ; China
  • 关键词:Aurora B ; c ; Myc ; Cisplatin ; Chemotherapy resistance ; Ovarian carcinoma ; Drug in combination
  • 刊名:Journal of Molecular Medicine
  • 出版年:2015
  • 出版时间:April 2015
  • 年:2015
  • 卷:93
  • 期:4
  • 页码:427-438
  • 全文大小:2,676 KB
  • 参考文献:1. Runnebaum, IB, Stickeler, E (2001) Epidemiological and molecular aspects of ovarian cancer risk. J Cancer Res Clin Oncol 127: pp. 73-79 CrossRef
    2. Agarwal, R, Kaye, SB (2003) Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 3: pp. 502-516 CrossRef
    3. Hollander, J, Rimpi, S, Doherty, JR, Rudelius, M, Buck, A, Hoellein, A, Kremer, M, Graf, N, Scheerer, M, Hall, MA (2010) Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state. Blood 116: pp. 1498-1505 CrossRef
    4. Zhang, L, Zhang, S (2011) ZM447439, the Aurora kinase B inhibitor, suppresses the growth of cervical cancer SiHa cells and enhances the chemosensitivity to cisplatin. J Obstet Gynaecol Res 37: pp. 591-600 CrossRef
    5. Qi, G, Ogawa, I, Kudo, Y, Miyauchi, M, Siriwardena, BS, Shimamoto, F, Tatsuka, M, Takata, T (2007) Aurora-B expression and its correlation with cell proliferation and metastasis in oral cancer. Virchows Arch 450: pp. 297-302 CrossRef
    6. Chen, YJ, Chen, CM, Twu, NF, Yen, MS, Lai, CR, Wu, HH, Wang, PH, Yuan, CC (2009) Overexpression of Aurora B is associated with poor prognosis in epithelial ovarian cancer patients. Virchows Arch 455: pp. 431-440 CrossRef
    7. Gautschi, O, Heighway, J, Mack, PC, Purnell, PR, Lara, PN, Gandara, DR (2008) Aurora kinases as anticancer drug targets. Clin Cancer Res 14: pp. 1639-1648 CrossRef
    8. Wilkinson, RW, Odedra, R, Heaton, SP, Wedge, SR, Keen, NJ, Crafter, C, Foster, JR, Brady, MC, Bigley, A, Brown, E (2007) AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis. Clin Cancer Res 13: pp. 3682-3688 CrossRef
    9. Ma, Y, Weimer, J, Fredrik, R, Adam-Klages, S, Sebens, S, Caliebe, A, Hilpert, F, Eckmann-Scholz, C, Arnold, N, Schem, C (2013) Aurora kinase inhibitor AZD1152 has an additional effect of platinum on a sequential application at the human ovarian cancer cell line SKOV3. Arch Gynecol Obstet 288: pp. 173-182 CrossRef
    10. Beussel, S, Hasenburg, A, Bogatyreva, L, Hauschke, D, Werner, M, Lassmann, S (2012) Aurora-B protein expression is linked to initial response to taxane-based first-line chemotherapy in stage III ovarian carcinoma. J Clin Pathol 65: pp. 29-35 CrossRef
    11. Mortlock, AA, Foote, KM, Heron, NM, Jung, FH, Pasquet, G, Lohmann, JJ, Warin, N, Renaud, F, Savi, C, Roberts, NJ (2007) Discovery, synthesis, and in vivo activity of a new class of pyrazoloquinazolines as selective inhibitors of aurora B kinase. J Med Chem 50: pp. 2213-2224 CrossRef
    12. Gully, CP, Zhang, F, Chen, J, Yeung, JA, Velazquez-Torres, G, Wang, E, Yeung, SC, Lee, MH (2010) Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer. Mol Cancer 9: pp. 42 CrossRef
    13. Ikezoe, T, Takeuchi, T, Yang, J, Adachi, Y, Nishioka, C, Furihata, M, Koeffler, HP, Yokoyama, A (2009) Analysis of Aurora B kinase in non-Hodgkin lymphoma. Lab Investig 89: pp. 1364-1373 CrossRef
    14. Ma, YX, Li, XZ (2013) Effect of aurora kinase B inhibitor AZD1152 in the treatment of cisplatin-resistant ovarian carcinoma. Zhonghua Fu Chan Ke Za Zhi 48: pp. 46-50
    15. Zhou, X, Fang, Y, Jing, H, Zhong, L, Luo, P, Song, H, Yang, B, He, Q (2013) Involvement of mitogen-activated protein kinase in signal transducer and activator of transcription-1 mediated differentiation induced by bortezomib in acute myeloid leukemia cells. Mol Carcinog 52: pp. 18-28 CrossRef
    16. Chou, TC, Talalay, P (1984) Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzym Regul 22: pp. 27-55 CrossRef
    17. Kang, MH, Kang, YH, Szymanska, B, Wilczynska-Kalak, U, Sheard, MA, Harned, TM, Lock, RB, Reynolds, CP (2007) Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo. Blood 110: pp. 2057-2066 CrossRef
    18. Vader, G, Lens, SM (2008) The Aurora kinase family in cell division and cancer. Biochim Biophys Acta 1786: pp. 60-72
    19. Havelka, AM, Berndtsson, M, Olofsson, MH, Shoshan, MC, Linder, S (2007) Mechanisms of action of DNA-damaging anticancer drugs in treatment of carcinomas: is acute apoptosis an "off-target" effect?. Mini Rev Med Chem 7: pp. 1035-1039 CrossRef
    20. Domcke S, Sinha R, Levine DA, Sander C, Schultz N (2013) Evaluating cell lines as tumour models by comparison of genomic profiles. Nat Commun 4. doi:Artn 2126 Doi 10.1038/Ncomms3126
    21. Boxer, LM, Dang, CV (2001) Translocations involving c-myc and c-myc function. Oncogene 20: pp. 5595-5610 CrossRef
    22. Hergeth, SP, Dundr, M, Tropberger, P, Zee, BM, Garcia, BA, Daujat, S, Schneider, R (2011) Isoform-specific phosphorylation of human linker histone H1.4 in mitosis by the kinase Aurora B. J Cell Sci 124: pp. 1623-1628 CrossRef
    23. Akiyama, M, Izumi, H, Wang, KY, Yamaguchi, T, Kuma, A, Kitamura, N, Harada, Y, Oya, R, Yamaguchi, K, Iwai, Y (2014) Hypersensitivity to Aurora kinase inhibitors in cells resistant against platinum-containing anticancer agents. Chem, Anticancer Agents Med
    24. Azzariti, A, Xu, JM, Porcelli, L, Paradiso, A (2004) The schedule-dependent enhanced cytotoxic activity of 7-ethyl-10-hydroxy-camptothecin (SN-38) in combination with Gefitinib (Iressa, ZD1839). Biochem Pharmacol 68: pp. 135-144 CrossRef
    25. Ditchfield, C, Johnson, VL, Tighe, A, Ellston, R, Haworth, C, Johnson, T, Mortlock, A, Keen, N, Taylor, SS (2003) Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol 161: pp. 267-280 CrossRef
    26. Nair, JS, Stanchina, E, Schwartz, GK (2009) The topoisomerase I poison CPT-11 enhances the effect of the aurora B kinase inhibitor AZD1152 both in vitro and in vivo. Clin Cancer Res 15: pp. 2022-2030 CrossRef
    27. Ganem, NJ, Pellman, D (2007) Limiting the proliferation of polyploid cells. Cell 131: pp. 437-440 CrossRef
    28. Nilsson, C, Roberg, K, Grafstrom, RC, Ollinger, K (2010) Intrinsic differences in cisplatin sensitivity of head and neck cancer cell lines: correlation to lysosomal pH. Head Neck 32: pp. 1185-1194 CrossRef
    29. Kaspers, GJ, Smets, LA, Pieters, R, Zantwijk, CH, Wering, ER, Veerman, AJ (1995) Favorable prognosis of hyperdiploid common acute lymphoblastic leukemia may be explained by sensitivity to antimetabolites and other drugs: results of an in vitro study. Blood 85: pp. 751-756
    30. Kokkinakis, DM, Brickner, AG, Kirkwood, JM, Liu, X, Goldwasser, JE, Kastrama, A, Sander, C, Bocangel, D, Chada, S (2006) Mitotic arrest, apoptosis, and sensitization to chemotherapy of melanomas by methionine deprivation stress. Mol Cancer Res 4: pp. 575-589 CrossRef
    31. Garte, SJ (1993) The c-myc oncogene in tumor progression. Crit Rev Oncog 4: pp. 435-449
    32. Darcy, KM, Brady, WE, Blancato, JK, Dickson, RB, Hoskins, WJ, McGuire, WP, Birrer, MJ (2009) Prognostic relevance of c-MYC gene amplification and polysomy for chromosome 8 in suboptimally-resected, advanced stage epithelial ovarian cancers: a Gynecologic Oncology Group study. Gynecol Oncol 114: pp. 472-479 CrossRef
    33. Kashani-Sabet, M, Wang, W, Scanlon, KJ (1990) Cyclosporin A suppresses cisplatin-induced c-fos gene expression in ovarian carcinoma cells. J Biol Chem 265: pp. 11285-11288
    34. Vaskivuo, L, Rysa, J, Koivupera, J, Myllynen, P, Vaskivuo, T, Chvalova, K, Serpi, R, Savolainen, ER, Puistola, U, Vahakangas, K (2006) Azidothymidine and cisplatin increase p14ARF expression in OVCAR-3 ovarian cancer cell line. Toxicol Appl Pharmacol 216: pp. 89-97 CrossRef
  • 刊物类别:Biomedical and Life Sciences
  • 刊物主题:Biomedicine
    Molecular Medicine
    Internal Medicine
  • 出版者:Springer Berlin / Heidelberg
  • ISSN:1432-1440
文摘
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.