A case of pancreatic neuroendocrine tumors

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• 作者：Masato Moriyama ; Yoshifumi Matsumoto…
• 关键词：Neuroendocrine tumor ; Lung metastasis ; Mediastinal lymph nodes swelling ; Radiotherapy
• 刊名：International Cancer Conference Journal
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：5
• 期：1
• 页码：1-4
• 全文大小：1,685 KB
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• 作者单位：Masato Moriyama (1)
  Yoshifumi Matsumoto (1)
  Qiliang Zhou (1)
  Kanako Yamana (2)
  Yohei Ikeda (2)
  Fumio Ayukawa (2)
  Eisuke Abe (2)
  Seijiro Sato (3)
  Kabuto Takano (4)
  Motoki Kaidu (2)
  Hidefumi Aoyama (2)
  Yasuo Saijo (1)
  
  1. Department of Medical Oncology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan
  2. Department of Radiology and Radiation Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
  3. Department of Thoracic Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
  4. Department of Digestive Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
  
• 刊物主题：Oncology; Surgical Oncology;
• 出版者：Springer Japan
• ISSN：2192-3183

文摘

Pancreatic neuroendocrine tumors (pNETs) are an uncommon malignancy arising from the neuroendocrine cells of pancreas. Most cases of pNETs present with metastatic disease, but there are few reports in the literature describing pNETs metastasis to the lung and mediastinal lymph nodes [1]. Moreover, although a multimodal treatment including surgical resection and chemotherapy is acceptable for management of pNETs, advanced pNETs still remain a difficult therapeutic challenge [2, 3]. Radiotherapy or combined chemoradiotherapy has not been standard in the treatment of pNETs. An 80-year-old female was admitted to our hospital with cough and anorexia. She had been diagnosed and resected pNETs 8 years ago. Mass shadow was pointed out with chest X-ray, and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) was performed. Pathological examination revealed neuroendocrine tumors, so the lung mass was considered as metastasis of pNETs. Then, we discussed her treatment at Cancer Board, and radiotherapy was chosen. We hope this case suggests that radiotherapy will be one of the treatment options for metastatic pNETs. Keywords Neuroendocrine tumor Lung metastasis Mediastinal lymph nodes swelling Radiotherapy