FDG PET/CT: EANM procedure guidelines for tumour imaging: version 2.0

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• 作者：Ronald Boellaard (1)
  Roberto Delgado-Bolton (2)
  Wim J. G. Oyen (3)
  Francesco Giammarile (4)
  Klaus Tatsch (5)
  Wolfgang Eschner (6)
  Fred J. Verzijlbergen (7)
  Sally F. Barrington (8)
  Lucy C. Pike (8)
  Wolfgang A. Weber (9)
  Sigrid Stroobants (10)
  Dominique Delbeke (11)
  Kevin J. Donohoe (12)
  Scott Holbrook (13)
  Michael M. Graham (14)
  Giorgio Testanera (15)
  Otto S. Hoekstra (1)
  Josee Zijlstra (16)
  Eric Visser (3)
  Corneline J. Hoekstra (17)
  Jan Pruim (18)
  Antoon Willemsen (18)
  Bertjan Arends (19)
  J枚rg Kotzerke (20)
  Andreas Bockisch (21)
  Thomas Beyer (22)
  Arturo Chiti (15)
  Bernd J. Krause (23)
  
  1. Department of Radiology & Nuclear Medicine ; VU University Medical Centre ; De Boelelaan 1117 ; 1081 HV ; Amsterdam ; The Netherlands
  2. Department of Diagnostic Imaging (Radiology) and Nuclear Medicine ; San Pedro Hospital and Centre for Biomedical Research of La Rioja (CIBIR) ; University of La Rioja ; Logro帽o ; La Rioja ; Spain
  3. Department of Radiology & Nuclear Medicine ; Radboud University Nijmegen Medical Centre ; Nijmegen ; The Netherlands
  4. Department of Nuclear Medicine ; Centre Hospitalier Universitaire de Lyon ; Lyon ; France
  5. Department of Nuclear Medicine ; Municipal Hospital Karlsruhe Inc. ; Karlsruhe ; Germany
  6. Department of Nuclear Medicine ; University of Cologne ; Cologne ; Germany
  7. Department of Nuclear Medicine ; Erasmus Medical Center ; Rotterdam ; The Netherlands
  8. PET Imaging Centre ; St Thomas鈥?Hospital ; Division of Imaging Sciences and Biomedical Engineering ; King鈥檚 College London ; King鈥檚 Health Partners ; London ; UK
  9. Department of Radiology ; Memorial Sloan Kettering Center ; New York ; NY ; USA
  10. Department of Nuclear Medicine ; Antwerp University Hospital ; Antwerp ; Belgium
  11. Department of Radiology and Radiological Sciences ; Vanderbilt University Medical Center ; Nashville ; TN ; USA
  12. Beth Israel Deaconess Medical Center ; Boston ; MA ; USA
  13. Invivo Molecular Imaging LLC ; Gray ; TN ; USA
  14. Department of Radiology ; University of Iowa ; Iowa City ; IA ; USA
  15. Department of Nuclear Medicine ; Humanitas Clinical and Research Center ; Rozzano ; MI ; Italy
  16. Department of Hematology ; VU University Medical Centre ; Amsterdam ; The Netherlands
  17. Department of Nuclear Medicine ; Jeroen Bosch Hospital ; Den Bosch ; The Netherlands
  18. Department of Nuclear Medicine & Molecular Imaging ; University Medical Centre Groningen ; Groningen ; The Netherlands
  19. Department of Clinical Physics ; Catharina Hospital ; Eindhoven ; The Netherlands
  20. Clinic and Outpatient Clinic for Nuclear Medicine ; University Hospital Dresden ; Dresden ; Germany
  21. Clinic for Nuclear Medicine ; University Hospital Essen ; Essen ; Germany
  22. Centre for Medical Physics and Biomedical Engineering ; Medical University of Vienna ; Vienna ; Austria
  23. Department of Nuclear Medicine ; University Hospital Rostock ; Rostock ; Germany
  
• 关键词：FDG ; PET/CT ; Imaging procedure ; Tumour ; Oncology ; Quantification
• 刊名：European Journal of Nuclear Medicine and Molecular Imaging
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：42
• 期：2
• 页码：328-354
• 全文大小：515 KB
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• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Nuclear Medicine
  Imaging and Radiology
  Orthopedics
  Cardiology
  Oncology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1619-7089

文摘

The purpose of these guidelines is to assist physicians in recommending, performing, interpreting and reporting the results of FDG PET/CT for oncological imaging of adult patients. PET is a quantitative imaging technique and therefore requires a common quality control (QC)/quality assurance (QA) procedure to maintain the accuracy and precision of quantitation. Repeatability and reproducibility are two essential requirements for any quantitative measurement and/or imaging biomarker. Repeatability relates to the uncertainty in obtaining the same result in the same patient when he or she is examined more than once on the same system. However, imaging biomarkers should also have adequate reproducibility, i.e. the ability to yield the same result in the same patient when that patient is examined on different systems and at different imaging sites. Adequate repeatability and reproducibility are essential for the clinical management of patients and the use of FDG PET/CT within multicentre trials. A common standardised imaging procedure will help promote the appropriate use of FDG PET/CT imaging and increase the value of publications and, therefore, their contribution to evidence-based medicine. Moreover, consistency in numerical values between platforms and institutes that acquire the data will potentially enhance the role of semiquantitative and quantitative image interpretation. Precision and accuracy are additionally important as FDG PET/CT is used to evaluate tumour response as well as for diagnosis, prognosis and staging. Therefore both the previous and these new guidelines specifically aim to achieve standardised uptake value harmonisation in multicentre settings.