Idiopathic Chronic Urticaria and Celiac Disease

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• 作者：Maurizio Gabrielli ; Marcello Candelli ; Filippo Cremonini ; Veronica Ojetti ; Luca Santarelli ; Enrico C. Nista ; Eleonora Nucera ; Domenico Schiavino ; Giampiero Patriarca and Giovanni Gasbarrini ; et al.
• 关键词：idiopathic chronic urticaria ; celiac disease ; anti ; transglutaminase antibodies ; anti ; endomysium antibodies ; autoimmune diseases
• 刊名：Digestive Diseases and Sciences
• 出版年：2005
• 出版时间：2005
• 年：2005
• 卷：50
• 期：9
• 页码：1702-1704
• 全文大小：37 KB

文摘

Idiopathic chronic urticaria (ICU) is a chronic relapsing cutaneous disease. Some case reports or studies on small series of celiac disease (CD) patients have suggested a possible association between CD and ICU. The aim of this study was to assess the prevalence of CD in a population of adults ICU patients with respect to healthy controls. We consecutively enrolled 80 patients affected by ICU and 264 blood donors as the control population without a history of ICU. Serum anti-transglutaminase IgG and anti-endomysium IgA antibodies were evaluated in all subjects. In the case of positivity to serology, diagnosis was confirmed by duodenal biopsy. One of 80 (1.25 % ) ICU patients were positive to both anti-transglutaminase and anti-endomysium antibodies. Duodenal biopsy showed partial villous atrophy. One control of 264 (0.38 % ) had CD. No statistical difference was found in the prevalence of CD between the two groups. ICU patients do not seem to bear a greater risk for CD compared to the general population.