Renal mucinous tubular and spindle cell carcinoma: two cases report and review of the literature

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• 作者：Zhifeng Wei (1)
  Zhengyu Zhang (1)
  Jingping Ge (1)
  Jianping Gao (1)
  Wenquan Zhou (1)
  
• 关键词：mucinous tubular and spindle cell carcinoma (MTSCC) ; kidney
• 刊名：The Chinese-German Journal of Clinical Oncology
• 出版年：2012
• 出版时间：November 2012
• 年：2012
• 卷：11
• 期：11
• 页码：672-675
• 全文大小：417KB
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  2. Simon RA, di Sant鈥檃gnese PA, Palapattu GS, / et al. Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid differentiation. Int J Clin Exp Pathol, 2008, 1: 180鈥?84.
  3. Srigley JR. Mucinous tubular and spindle cell carcinoma. In: Eble JN, Sauter G, eds. World Health Organization Classification of Tumor. Tumors of the Urinary System and Male Genital Organs. Lyon: IARC Press, 2004. 40.
  4. Jung SJ, Yoon HK, Chung JI, / et al. Mucinous tubular and spindle cell carcinoma of the kidney with neuroendocrine differentiation: report of two cases. Am J Clin Pathol, 2006, 125: 99鈥?04.
  5. Kato M, Soga N, Arima K, / et al. A case of renal mucinous tubular and spindle cell carcinoma. Int J Urol, 2009, 8: 699鈥?01. CrossRef
  6. Hes O, Hora M, Perez-Montiel DM, / et al. Spindle and cuboidal renal cell carcinoma, a tumour having frequent association with nephrolithiasis: report of 11 cases including a case with hybrid conventional renal cell carcinoma/spindle and cuboidal renal cell carcinoma components. Histopathology, 2002, 6: 549鈥?55. CrossRef
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  11. Pillay N, Ramdial PK, Cooper K, / et al. Mucinous tubular and spindle cell carcinoma with aggressive histomorphology-a sarcomatoid variant. Hum Pathol, 2008, 39: 966鈥?69. CrossRef
  12. Paner GP, Srigley JR, Radhakrishnan A, / et al. Immunohistochemical analysis of mucinous tubular and spindle cell carcinoma and papillary renal cell carcinoma of the kidney: significant immunophenotypic overlap warrants diagnostic caution. Am J Surg Pathol, 2006, 30: 13鈥?9. CrossRef
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  14. Han K, Sun YJ, Zhang JJ, / et al. Retrospective clinical analysis of MAID protocol as first-line treatment on 137 metastatic soft-tissue sarcomas patients. Chinese-German J Clin Oncol, 2012, 2: 117鈥?20. CrossRef
  
• 作者单位：Zhifeng Wei (1)
  Zhengyu Zhang (1)
  Jingping Ge (1)
  Jianping Gao (1)
  Wenquan Zhou (1)
  
  1. Department of Urology, Jinling Hospital, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing, 210002, China
  

文摘

We reported the clinical and pathologic features of two different types of renal mucinous tubular and spindle cell carcinoma (MTSCC). The first patient was incidentally discovered by health examination, with lower nuclear grade, no part and distant metastasis. The second patient presented with persistence hyperpyrexia, part and distant metastasis, and high nuclear grade. Surgery were both performed successfully. The first patient had no recurrences and no distant metastases. The second patient died of multiple organ failure 3 months postoperatively. Although MTSCC is usually a low potential malignancy carcinoma, high malignancy may occur and lead to a fatal course. So it needs a proper management and prognostication.