First-dose and steady-state pharmacokinetics of orally administered crizotinib in children with solid tumors: a report on ADVL0912 from the Children’s Oncology Group Phase 1/Pilot Consortium

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First-dose and steady-state pharmacokinetics of orally administered crizotinib in children with solid tumors: a report on ADVL0912 from the Children’s Oncology Group Phase 1/Pilot Consortium

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作者：Frank M. Balis ; Patrick A. Thompson ; Yael P. Mosse…
关键词：Crizotinib ; Pharmacokinetics ; Childhood cancer ; Children ; ALK
刊名：Cancer Chemotherapy and Pharmacology
出版年：2017
出版时间：January 2017
年：2017
卷：79
期：1
页码：181-187
全文大小：1332KB
刊物类别：Biomedical and Life Sciences
刊物主题：Oncology; Pharmacology/Toxicology; Cancer Research;
出版者：Springer Berlin Heidelberg
ISSN：1432-0843
卷排序：79

文摘

PurposeCharacterize the pharmacokinetics of oral crizotinib in children with cancer.