Serum antibody levels against Porphyromonas gingivalis in patients with and without rheumatoid arthritis – a systematic review and meta-analysis

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• 作者：Philip Bender ; Walter B. Bürgin ; Anton Sculean ; Sigrun Eick
• 关键词：Porphyromonas gingivalis ; Periodontal disease ; Rheumatoid arthritis ; Serum antibody levels
• 刊名：Clinical Oral Investigations
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：21
• 期：1
• 页码：33-42
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Dentistry;
• 出版者：Springer Berlin Heidelberg
• ISSN：1436-3771
• 卷排序：21

文摘

ObjectivesSince the peptidyl arginine deiminase of Porphyromonas gingivalis is able to citrullinate peptides and proteins, various studies have suggested the species as a possible link between periodontal disease (PD) and rheumatoid arthritis (RA). This systematic review including meta-analysis was aimed to evaluate whether differences in terms of antibody titers against P. gingivalis exist between RA patients and systemically healthy individuals with and without PD.