Distribution and frequency of G119S mutation in ace-1 gene within Anopheles sinensis populations from Guangxi, China

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• 作者：Xiangyang Feng ; Chan Yang ; Yichao Yang ; Jun Li ; Kangming Lin ; Mei Li…
• 关键词：Acetyl ; cholinesterase ; Anopheles sinensis ; G119S mutation ; Guangxi Zhuang Autonomous Region of China ; Organophosphate ; Carbamate ; Insecticide resistance
• 刊名：Malaria Journal
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：14
• 期：1
• 全文大小：1,406 KB
• 刊物主题：Parasitology; Infectious Diseases; Tropical Medicine;
• 出版者：BioMed Central
• ISSN：1475-2875

文摘

Background Malaria is one of the most serious vector-borne diseases in the world. Vector control is an important measure for malaria prevention and elimination. However, this strategy is under threat as disease vectors are developing resistance to insecticides. Therefore, it is important to monitor mechanisms responsible for insecticide resistance. In this study, the presence of G119S mutation in the acetyl cholinesterase-encoding gene (ace-1) was investigated in nine Anopheles sinensis populations sampled across Guangxi Zhuang Autonomous Region China.