Functional expression of a human GDP-l-fucose transporter in Escherichia coli

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• 作者：Karin Förster-Fromme ; Sarah Schneider ; Georg A. Sprenger…
• 关键词：Fucosylation ; GDP ; l ; fucose ; Glycoprotein synthesis ; Inverted membrane vesicle ; Nucleotide sugar transporter ; Escherichia coli
• 刊名：Biotechnology Letters
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：39
• 期：2
• 页码：219-226
• 全文大小：
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Microbiology; Biotechnology; Applied Microbiology; Biochemistry, general;
• 出版者：Springer Netherlands
• ISSN：1573-6776
• 卷排序：39

文摘

ObjectivesTo investigate the translocation of nucleotide-activated sugars from the cytosol across a membrane into the endoplasmatic reticulum or the Golgi apparatus which is an important step in the synthesis of glycoproteins and glycolipids in eukaryotes.