Benzazoles 5*. Synthesis and arylsulfonylation of 1-hydroxymethylbenzimidazole

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• 作者：K. B. Abdireimov (1)
  N. S. Mukhamedov (1) nasirxon@rambler.ru
  M. Zh. Aiymbetov (1)
  Kh. M. Shakhidoyatov (1)
• 关键词：1 ; arylsulfonylbenzimidazoles – ; 1 ; hydroxymethylbenzimidazole – ; arylsulfonylation – ; hydroxy ; methylation – ; deformylation
• 刊名：Chemistry of Heterocyclic Compounds
• 出版年：2012
• 出版时间：June 2012
• 年：2012
• 卷：48
• 期：3
• 页码：458-461
• 全文大小：334.1 KB
• 参考文献：1. M. E. Karimova, D. A. Dushamov, R. Sh. Kuryazov, and N. S. Mukhamedov, Khim. Geterotsikl. Soedin., 117 (2011). [ Chem. Heterocycl. Compd., 47, 90 (2011)].
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• 作者单位：1. S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of Uzbekistan, 77 Mirzo Ulugbek Ave., Tashkent, 100170 Uzbekistan
• ISSN：1573-8353

文摘

1-Hydroxymethylbenzimidazole was synthesized by the reaction of benzimidazole with formaldehyde. Arylsulfonylation of the former in the presence of triethylamine occurred anomalously with deformylation to give 1-arylsulfonylbenzimidazoles in place of the expected 1-arylsulfonyloxymethyl-benzimidazoles.