Autoantibodies to central nervous system neuronal surface antigens: psychiatric symptoms and psychopharmacological implications

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• 作者：T. A. Pollak ; K. Beck ; S. R. Irani ; O. D. Howes ; A. S. David…
• 关键词：Antibody ; Immunoreactivity ; Inflammation ; Receptor ; NMDA receptor ; Potassium channel ; GABA receptor ; Limbic system
• 刊名：Psychopharmacology
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：233
• 期：9
• 页码：1605-1621
• 全文大小：572 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Pharmacology and Toxicology
  Psychiatry
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-2072

文摘

Rationale Autoantibodies to central nervous system (CNS) neuronal surface antigens have been described in association with autoimmune encephalopathies which prominently feature psychiatric symptoms in addition to neurological symptoms. The potential role of these autoantibodies in primary psychiatric diseases such as schizophrenia or bipolar affective disorder is of increasing interest.