Sensitivity response to coating material thickness for an optical resonant reflective biosensor based on a guided mode resonance filter

详细信息    查看全文

• 作者：Bong Kyu Kim (1)
  Kyung-Hyun Kim (1)
  Jongcheol Hong (1)
  Wan-Joong Kim (1)
  Hyunsung Ko (1)
  Chul Huh (1)
  Gun Yong Sung (2)
  Won Ick Jang (1)
  Sun Hee Park (1)
  Soo Jun Park (1)
  
• 关键词：Biosensor ; Optical resonance reflection biosensor ; Guided mode reflection filter ; Sensitivity ; Nanostructure
• 刊名：BioChip Journal
• 出版年：2014
• 出版时间：March 2014
• 年：2014
• 卷：8
• 期：1
• 页码：35-41
• 全文大小：404 KB
• 参考文献：1. Bosch, M.E., Sanchez, A.J.R, Rojas, F.S. & Ojeda, C.B. Recent development in optical fiber biosensors. / Sensors 7, 797鈥?59 (2007). CrossRef
  2. Lim, S.C. / et al. Fabrication and characterization of an OTFT-based biosensor using a biotinylated F8T2 polymer. / ETRI J. 31, 647鈥?52 (2009). CrossRef
  3. Tubb, A.J.C., Payne, F.P., Millington, R.B. & Lowe, C.R. Single-mode optical fibre surface plasma wave chemical sensor. / Sensors and Actuators B 41, 71鈥?9 (1997). CrossRef
  4. Magnusson, R. & Wang, S.S. New principle for optical filters, / Appl. Phys. Lett. 61, 1022鈥?024 (1992). CrossRef
  5. Wang, S.S. & Magnusson, R. Theory and applications of guided-mode resonance filter. / Appl. Opt. 32, 2606鈥?613 (1993). CrossRef
  6. Mashev, L. & Popov, E. Zero order anomaly of dielectric coated gratings. / Opt. Communications 55, 377鈥?79 (1985). CrossRef
  7. Boye, R.R. & Kostuk, R.K. Investigation of the effect of finite grating size on the performance of guidedmode resonance filter. / Appl. Opt. 39, 3649鈥?653 (2000). CrossRef
  8. Song, H.Y., Kim, S. & Magnusson, R. Tunable guidedmode resonances in coupled grating. / Opt. Express 17, 23544鈥?3555 (2009). CrossRef
  9. Ngo, Q.M., Kim, S., Song, S.H. & Magnusson, R. Optical bistable devices based on guided-mode resonance in slab waveguide grating. / Opt. Express 17, 23459鈥?3467 (2009). CrossRef
  10. Chang, A.S.P. / et al. Tunable liquid crystal-resonant grating filter fabricated by nanoimprint lithography. / IEEE Photonics Technology Letters 19, 1457鈥?459 (2007). CrossRef
  11. Wawro, D.D., Tibuleac, S., Magnusson, R. & Liu, H. Optical fiber endface biosensor based on resonance in dielectric waveguide gratings. / Proc. of SPIE 3911, 86鈥?4 (2000). CrossRef
  12. Block, I.D., Ganesh, N., Meng. L. & Cunningham, B.T. A sensitivity model for predicting photonics crystal biosensor performance. / IEEE Sensors Journal 8, 274鈥?80 (2008). CrossRef
  13. Hong, J. / et al. Prediction of the limit of detection of an optical resonant reflection biosensor. / Opt. Express 15, 8972鈥?978 (2007). CrossRef
  14. Magnusson, R. / et al. Photonic devices enabled by waveguide-mode resonance effects in periodically modulated films. / Proc. SPIE 5225, 20鈥?4 (2003). CrossRef
  15. Gsolver漏 V5.1 Diffraction Grating Analysis Program. http://www.gsolver.com/brochureV51.pdf.
  16. Adams, M.J. An introduction to optical waveguides (John Wiley and Sons Ltd., New York, pp. 20鈥?8, 1981).
  
• 作者单位：Bong Kyu Kim (1)
  Kyung-Hyun Kim (1)
  Jongcheol Hong (1)
  Wan-Joong Kim (1)
  Hyunsung Ko (1)
  Chul Huh (1)
  Gun Yong Sung (2)
  Won Ick Jang (1)
  Sun Hee Park (1)
  Soo Jun Park (1)
  
  1. Bio-medical IT Convergence Department, ETRI, Yusong-Gu, Daejeon, 305-701, Korea
  2. Department of Materials Science & Engineering, College of Information & Electronic Engineering, Hallym University, Seoul, Korea
  
• ISSN：2092-7843

文摘

Sensitivity is a very important parameter for biosensor applications. We have numerically and experimentally studied the sensitivity and linewidth responses of optical resonant reflective biosensors to the thickness of high refractive index materials coating the grating layer used to create a guided mode. Zero sensitivity, which may create serious problems in biosensors, is obtained when the coating material has a relatively low refractive index and a thin coating thickness (near the cutoff condition in which a high index layer is no longer capable of acting as a waveguide). The sensitivity and linewidth are greatly influenced by the thickness of the coating material. The thickness also has an optimal state, which is a very important factor for designing highly sensitive optical resonant reflective biosensors using a guided mode resonance filter.