Saliva DNA quality and genotyping efficiency in a predominantly elderly population

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• 作者：Harini V. Gudiseva ; Mark Hansen ; Linda Gutierrez ; David W. Collins…
• 关键词：Saliva ; Blood ; DNA ; Genotyping ; Microarrays ; GWAS ; SNPs ; Elderly ; Glaucoma ; African ; Americans ; 260/280 absorbance ; Call rates
• 刊名：BMC Medical Genomics
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：9
• 期：1
• 全文大小：1,146 KB
• 刊物主题：Human Genetics; Microarrays;
• 出版者：BioMed Central
• ISSN：1755-8794

文摘

Background The question of whether DNA obtained from saliva is an acceptable alternative to DNA from blood is a topic of considerable interest for large genetics studies. We compared the yields, quality and performance of DNAs from saliva and blood from a mostly elderly study population.