Hepatic iron storage is related to body adiposity and hepatic inflammation

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• 作者：Chan Yoon Park ; Jayong Chung ; Kyung-Ok Koo ; Min Soo Kim…
• 关键词：Hepatic non ; heme iron ; Mild calorie restriction ; Iron absorption ; Duodenal iron transporter ; Hepcidin ; Body adiposity
• 刊名：Nutrition & Metabolism
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：14
• 期：1
• 全文大小：735KB
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Clinical Nutrition; Metabolic Diseases;
• 出版者：BioMed Central
• ISSN：1743-7075
• 卷排序：14

文摘

BackgroundObesity has been reported to be associated with iron deficiency. However, few studies have investigated iron status in low adiposity. To investigate whether body adiposity was associated with altered hepatic iron status, we compared liver iron levels and markers involved in inflammation and iron absorption in obese, control, and mildly calorie restricted mice.