Use of ethanol extracts of Terminalia chebula to prevent periodontal disease induced by dental plaque bacteria

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• 作者：Jongsung Lee ; Youn Hwa Nho ; Seok Kyun Yun…
• 关键词：Ethanol extract of Terminalia chebula (EETC) ; Gingivitis ; Periodontitis ; Dental plaque bacteria (DPB) ; Lipopolysaccharide (LPS) ; Inflammation ; Osteoclast
• 刊名：BMC Complementary and Alternative Medicine
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：4116KB
• 刊物主题：Complementary & Alternative Medicine; Internal Medicine; Chiropractic Medicine;
• 出版者：BioMed Central
• ISSN：1472-6882
• 卷排序：17

文摘

BackgroundThe fruit of the Terminalia chebula tree has been widely used for the treatment of various disorders. Its anti-diabetic, anti-mutagenic, anti-oxidant, anti-bacterial, anti-fungal, and anti-viral effects have been studied. Dental plaque bacteria (DPB) are intimately associated with gingivitis and periodontitis. In the quest for materials that will prove useful in the treatment and prevention of periodontal disease, we investigated the preventive effects of an ethanol extract of Terminalia chebula (EETC) on DPB-induced inflammation and bone resorption.