Role of olanzapine in chemotherapy-induced nausea and vomiting on platinum-based chemotherapy patients: a randomized controlled study

详细信息    查看全文

• 作者：Sandip Mukhopadhyay ; Gagandeep Kwatra ; Pamela Alice K…
• 关键词：Olanzapine ; Chemotherapy ; induced nausea and vomiting ; Platinum compounds ; Palonosetron
• 刊名：Supportive Care in Cancer
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：25
• 期：1
• 页码：145-154
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Oncology; Nursing; Nursing Research; Pain Medicine; Rehabilitation Medicine;
• 出版者：Springer Berlin Heidelberg
• ISSN：1433-7339
• 卷排序：25

文摘

PurposeEven with the use of modern antiemetic drugs, chemotherapy-induced nausea and vomiting (CINV) is still a cause of great distress to the patients. Olanzapine, primarily marketed as an antipsychotic, was found to reduce nausea and vomiting in some chemotherapy patients. But it was never tested in Indian population with a diverse genetic background. The present study aims to evaluate the role of olanzapine in CINV in patients receiving platinum-based chemotherapy.