Upregulation of interleukin-33 and thymic stromal lymphopoietin levels in the lungs of idiopathic pulmonary fibrosis

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• 作者：Jong-Uk Lee ; Hun Soo Chang ; Hyeon Ju Lee ; Chang An Jung&#8230
• 关键词：IL ; 25 ; IL ; 33 ; TSLP ; IPF ; Innate immune response
• 刊名：BMC Pulmonary Medicine
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：611KB
• 刊物主题：Pneumology/Respiratory System; Internal Medicine; Intensive / Critical Care Medicine;
• 出版者：BioMed Central
• ISSN：1471-2466
• 卷排序：17

文摘

BackgroundInnate T helper type 2 (Th2) immune responses mediated by interleukin (IL)-33, thymic stromal lymphopoietin (TSLP), and IL-25 have been shown to play an important role in pulmonary fibrosis of animal models; however, their clinical implications remain poorly understood.