Sheehan's syndrome: new insights into an old disease

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Sheehan's syndrome: new insights into an old disease

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作者：Halit Diri ; Zuleyha Karaca ; Fatih Tanriverdi ; Kursad Unluhizarci…
关键词：Sheehan’s syndrome ; Postpartum hemorrhage ; Pituitary insufficiency ; Hypopituitarism
刊名：Endocrine
出版年：2016
出版时间：January 2016
年：2016
卷：51
期：1
页码：22-31
全文大小：611 KB
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作者单位：Halit Diri (1)
Zuleyha Karaca (1)
Fatih Tanriverdi (1)
Kursad Unluhizarci (1)
Fahrettin Kelestimur (1)

1. Department of Endocrinology, Erciyes University Medical School, 38039, Kayseri, Turkey
刊物主题：Endocrinology; Diabetes; Internal Medicine; Science, general;
出版者：Springer US
ISSN：1559-0100

文摘

Sheehan’s syndrome (SS) is a parturition-related pituitary disease resulting from severe postpartum hemorrhage and can present with varying degrees of pituitary insufficiency. Pathological and clinical findings of SS were first described by Harold L. Sheehan in the previous century. Although his definitions are still valid, various studies and reports including new data have subsequently been published. Additionally, the diagnosis of SS has often been overlooked and thus delayed for long years due to its nonspecific signs and symptoms. Therefore, a large number of patients may be remained undiagnosed and untreated. SS is not as rare as assumed in developed countries, probably due to migrant women and unawareness of physicians regarding the syndrome. In this review, we provide a detailed review of the epidemiology, etiopathogenesis, clinical, laboratory and radiological features, new diagnostic criteria, differential diagnosis, and treatment of SS.