Two-year changes in generic and obesity-specific quality of life after gastric bypass

详细信息    查看全文

• 作者：Javier Mar (1) (2)
  Jan Karlsson (3)
  Arantzazu Arrospide (7)
  Blanca Mar (4)
  Gabriel Martez de Arag (5)
  Cdido Martinez-Blazquez (5)
  
• 关键词：Morbid obesity ; Gastric bypass ; Quality of life ; Disability ; ROC curves
• 刊名：Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity
• 出版年：2013
• 出版时间：September 2013
• 年：2013
• 卷：18
• 期：3
• 页码：305-310
• 全文大小：
• 作者单位：Javier Mar (1) (2)
  Jan Karlsson (3)
  Arantzazu Arrospide (7)
  Blanca Mar (4)
  Gabriel Martez de Arag (5)
  Cdido Martinez-Blazquez (5)
  
  1. Clinical Management Service, Alto Deba Hospital, Mondragon, Spain
  2. Health Research Unit (West Gipuzkoa), Alto Deba Hospital, Avenida Navarra 16, 20500, Mondragon, Spain
  3. Centre for Health Care Sciences, Department of Medicine, School of Health and Medical Sciences, rebro University Hospital, rebro, Sweden
  7. Health Research Unit (AP-OSIs Gipuzkoa), Alto Deba Hospital, Avenida Navarra 16, 20500, Mondragon, Spain
  4. Surgery Department, Donostia Hospital, Donostia-San Sebasti, Spain
  5. Surgery Department, Txagorritxu Hospital, Vitoria-Gasteiz, Spain
  
• ISSN：1590-1262

文摘

The study objectives were to assess 2-year changes in health-related quality of life (HRQL) after gastric bypass in patients with severe obesity and to analyze HRQL improvements in relation to weight loss after bariatric surgery. This was a prospective intervention study with consecutive patients referred to two bariatric surgical units in the Basque Country. We used both generic (Short Form Health Survey, SF-36 and EuroQol, EQ-5D), and specific questionnaires (Moorehead-Ardelt, MA II and Obesity-related Problems Scale, OP). Effect sizes and receiver operating characteristic (ROC) curves were calculated to assess the change in quality of life. Spearman correlation coefficient was calculated to assess whether there was an association between changes in body mass index (BMI) and HRQL. Of 82 patients who underwent surgery, 79 were followed-up for 2years. Mean weight loss was 37% of body weight (49kg) and BMI fell from 50.6 to 31.8. The initial problems and final improvements were greater in the physical dimensions. Considerable benefits were observed in assessments with all the instruments used. However, the changes in weight/BMI and HRQL were not linear. The comparison with general population showed a similar profile in SF-36 dimensions after surgery. Severely obese patients have lower perceived health across all dimensions of quality of life. Moreover, the impact on functioning is so important that severe obesity can be described as a cause of disability that disappears 2years after surgical treatment. ROC curves indicate that most of the HRQL measures are poor predictors of change in terms of reduction in body weight or BMI.