Efficacy of vitamin E and N-acetylcysteine in the prevention of contrast induced kidney injury in patients with chronic kidney disease: a double blind, randomized controlled trial
详细信息    查看全文
  • 作者：Thomas M. Kitzler M.D. (1)
    Aala Jaberi M.D. (2)
    Gerald Sendlhofer M.D. (3)
    Peter Rehak M.D. (4)
    Christian Binder M.D. (5)
    Eva Petnehazy M.D. (6)
    Rudolf Stacher M.D. (5)
    Peter Kotanko M.D. (5) (7) (8)
  • 关键词：Computer ; assisted tomography ; Contrast induced acute kidney injury ; N ; acetylcysteine ; Randomized controlled trial ; Vitamin E ; Chronic kidney disease ; Computertomographie 鈥?Kontrastmittelnephropathie ; N ; Acetylcysteine ; Randomisierte klinische Studie ; Vitamin E ; Chronische Niereninsuffizienz
  • 刊名：Wiener klinische Wochenschrift
  • 出版年：2012
  • 出版时间：May 2012
  • 年：2012
  • 卷：124
  • 期：9-10
  • 页码：312-319
  • 全文大小：863KB
  • 参考文献：1. McCullough PA, Sandberg KR. Epidemiology of contrast-induced nephropathy. Rev Cardiovasc Med. 2003;4 (Suppl 5):S3鈥?.
    2. Mehran R, Nikolsky E. Contrast-induced nephropathy: definition, epidemiology, and patients at risk. Kidney Int Suppl. 2006;100:S11鈥?. CrossRef
    3. McCullough PA. Contrast-induced acute kidney injury. J Am Coll Cardiol. 2008;51:1419鈥?8. CrossRef
    4. From AM, Bartholmai BJ, Williams AW, Cha SS, Pflueger A, McDonald FS. Sodium bicarbonate is associated with an increased incidence of contrast nephropathy: a retrospective cohort study of 7977 patients at mayo clinic. Clin J Am Soc Nephrol. 2008;3:10鈥?8. CrossRef
    5. Persson PB, Hansell P, Liss P. Pathophysiology of contrast medium-induced nephropathy. Kidney Int. 2005;68:14鈥?2. CrossRef
    6. McCullough PA, Soman SS. Contrast-induced nephropathy. Crit Care Clin. 2005;21:261鈥?0. CrossRef
    7. Brezis M, Rosen S. Hypoxia of the renal medulla鈥搃ts implications for disease. N Engl J Med. 1995;332:647鈥?5. CrossRef
    8. Arakawa K, Suzuki H, Naitoh M, Matsumoto A, Hayashi K, Matsuda H, et al. Role of adenosine in the renal responses to contrast medium. Kidney Int. 1996;49:1199鈥?206. CrossRef
    9. Workman RJ, Shaff MI, Jackson RV, Diggs J, Frazer MG, Briscoe C. Relationship of renal hemodynamic and functional changes following intravascular contrast to the renin-angiotensin system and renal prostacyclin in the dog. Invest Radiol. 1983;18:160鈥?. CrossRef
    10. Liss P, Nygren A, Olsson U, Ulfendahl HR, Erikson U. Effects of contrast media and mannitol on renal medullary blood flow and red cell aggregation in the rat kidney. Kidney Int. 1996;49:1268鈥?5. CrossRef
    11. Nygren A, Ulfendahl HR, Hansell P, Erikson U. Effects of intravenous contrast media on cortical and medullary blood flow in the rat kidney. Invest Radiol. 1988;23:753鈥?1. CrossRef
    12. Bakris GL, Lass NA, Glock D. Renal hemodynamics in radiocontrast medium-induced renal dysfunction: a role for dopamine-1 receptors. Kidney Int. 1999;56:206鈥?0. CrossRef
    13. Stone GW, McCullough PA, Tumlin JA, Lepor NE, Madyoon H, Murray P, et al. Fenoldopam mesylate for the prevention of contrast-induced nephropathy: a randomized controlled trial. JAMA. 2003;290:2284鈥?1. CrossRef
    14. Juncos R, Garvin JL. Superoxide enhances Na-K-2Cl cotransporter activity in the thick ascending limb. Am J Physiol Renal Physiol. 2005;288:F982鈥?. CrossRef
    15. Wellman TL, Jenkins J, Penar PL, Tranmer B, Zahr R, Lounsbury KM. Nitric oxide and reactive oxygen species exert opposing effects on the stability of hypoxia-inducible factor-1alpha (HIF-1alpha) in explants of human pial arteries. FASEB J. 2004;18:379鈥?1.
    16. Drager LF, Andrade L, Barros de Toledo JF, Laurindo FR, Machado Cesar LA, Seguro AC. Renal effects of N-acetylcysteine in patients at risk for contrast nephropathy: decrease in oxidant stress-mediated renal tubular injury. Nephrol Dial Transplant. 2004;19:1803鈥?. CrossRef
    17. Sandhu C, Newman DJ, Morgan R, Belli AM, Oliveira D. The role of oxygen free radicals in contrast induced nephrotoxicity. Acad Radiol. 2002;9 (Suppl 2):S436鈥?. CrossRef
    18. Palm F, Cederberg J, Hansell P, Liss P, Carlsson PO. Reactive oxygen species cause diabetes-induced decrease in renal oxygen tension. Diabetologia. 2003;46:1153鈥?0. CrossRef
    19. Abd-El-Fattah AA, El-Sawalhi MM, Rashed ER, El-Ghazaly MA. Possible role of vitamin E, coenzyme Q10 and rutin in protection against cerebral ischemia/reperfusion injury in irradiated rats. Int J Radiat Biol. 2010;86:1070鈥?. CrossRef
    20. Abu-Amara M, Gurusamy K, Hori S, Glantzounis G, Fuller B, Davidson BR. Systematic review of randomized controlled trials of pharmacological interventions to reduce ischaemia-reperfusion injury in elective liver resection with vascular occlusion. HPB (Oxford). 2010;12:4鈥?4. CrossRef
    21. Pflueger A, Abramowitz D, Calvin AD. Role of oxidative stress in contrast-induced acute kidney injury in diabetes mellitus. Med Sci Monit. 2009;15:RA125鈥?6.
    22. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med. 1999;130:461鈥?0.
    23. Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF 3rd, Feldman HI, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150:604鈥?2.
    24. Tepel M, Van Der Giet M, Schwarzfeld C, Laufer U, Liermann D, Zidek W. Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine. N Engl J Med. 2000;343:180鈥?. CrossRef
    25. Amini M, Salarifar M, Amirbaigloo A, Masoudkabir F, Esfahani F. N-acetylcysteine does not prevent contrast-induced nephropathy after cardiac catheterization in patients with diabetes mellitus and chronic kidney disease: a randomized clinical trial. Trials. 2009;10:45. CrossRef
    26. Calvin AD, Misra S, Pflueger A. Contrast-induced acute kidney injury and diabetic nephropathy. Nat Rev Nephrol. 2010;6:679鈥?8. CrossRef
    27. Marenzi G, Assanelli E, Marana I, Lauri G, Campodonico J, Grazi M, et al. N-acetylcysteine and contrast-induced nephropathy in primary angioplasty. N Engl J Med. 2006;354:2773鈥?2. CrossRef
    28. Rigotti A. Absorption, transport, and tissue delivery of vitamin E. Mol Aspects Med. 2007;28:423鈥?6. CrossRef
    29. Nakamura T, Aoyama Y, Fujita T, Katsui G. Studies on tocopherol derivatives: V. Intestinal absorption of several d,1鈥?,4鈥?H2-alpha-tocopheryl esters in the rat. Lipids. 1975;10:627鈥?3. CrossRef
    30. Traber MG, Goldberg I, Davidson E, Lagmay N, Kayden HJ. Vitamin E uptake by human intestinal cells during lipolysis in vitro. Gastroenterology. 1990;98:96鈥?03.
    31. Tasanarong A, Piyayotai D, Thitiarchakul S. Protection of radiocontrast induced nephropathy by vitamin E (alpha tocopherol): a randomized controlled pilot study. J Med Assoc Thai. 2009;92:1273鈥?1.
    32. Briguori C, Airoldi F, D鈥橝ndrea D, Bonizzoni E, Morici N, Focaccio A, et al. Renal Insufficiency Following Contrast Media Administration Trial (REMEDIAL): a randomized comparison of 3 preventive strategies. Circulation. 2007;115:1211鈥?.
  • 作者单位：Thomas M. Kitzler M.D. (1)
    Aala Jaberi M.D. (2)
    Gerald Sendlhofer M.D. (3)
    Peter Rehak M.D. (4)
    Christian Binder M.D. (5)
    Eva Petnehazy M.D. (6)
    Rudolf Stacher M.D. (5)
    Peter Kotanko M.D. (5) (7) (8)

    1. Department of Human Genetics, The Research Institute of the McGill University Health Centre at The Montreal Children鈥檚 Hospital, McGill University, 4060 St. Catherine Street West, Room 413, H3Z 2Z3, Montreal, QC, Canada
    2. Department of Medicine, Lyman Duff Medical Building, McGill University, 3775 University Street, Room 230, H3A 2B4, Montreal, QC, Canada
    3. Department of Quality Management, LKH-Univ. Klinikum Graz, Auenbruggerplatz 1, 8036, Graz, Austria
    4. Department of Surgery, Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria
    5. Krankenhaus der Barmherzigen Br眉der, Marschallgasse 12, 8020, Graz, Austria
    6. Krankenhaus der Barmherzigen Br眉der, Bergstrasse 27, 8020, Graz, Austria
    7. Renal Research Institute, 207 East 94th Street, Suite 303, 10128, New York, NY, USA
    8. Beth Israel Medical Center, 1st Avenue, 16th Street, 10003, New York, NY, USA
文摘
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.