Casticin induces apoptosis and G0/G1 cell cycle arrest in gallbladder cancer cells

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• 作者：Xiao-ling Song ; Yun-jiao Zhang ; Xue-feng Wang ; Wen-jie Zhang…
• 关键词：Casticin ; Gallbladder cancer ; Akt signaling pathway ; G0/G1 arrest ; Apoptosis
• 刊名：Cancer Cell International
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：6643KB
• 刊物主题：Cancer Research; Cell Biology;
• 出版者：BioMed Central
• ISSN：1475-2867
• 卷排序：17

文摘

BackgroundCasticin, the flavonoid extracted from Vitex rotundifolia L, exerts various biological effects, including anti-inflammatory and anti-cancer activity. The aim of this study is to investigate the effects and mechanisms of casticin in human gallbladder cancer cells.