Arrhythmias in Adult Congenital Patients With Bodily Isomerism

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• 作者：Rohit S. Loomba ; Saurabh Aggarwal ; Navdeep Gupta ; Matthew Buelow…
• 关键词：Arrhythmias ; Isomerism ; Heterotaxy ; Atrioventricular block ; Supraventricular tachycardia ; Conduction
• 刊名：Pediatric Cardiology
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：37
• 期：2
• 页码：330-337
• 全文大小：363 KB
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• 作者单位：Rohit S. Loomba (1)
  Saurabh Aggarwal (2)
  Navdeep Gupta (1)
  Matthew Buelow (1)
  Venkata Alla (2)
  Rohit R. Arora (3)
  Robert H. Anderson (4)
  
  1. Medical College of Wisconsin, Milwaukee, WI, USA
  2. Creighton University Medical Center, Omaha, NE, USA
  3. Chicago Medical School, North Chicago, IL, USA
  4. Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Cardiology
  Cardiac Surgery
  Vascular Surgery
  
• 出版者：Springer New York
• ISSN：1432-1971

文摘

There are an increasing number of adults with congenital heart disease, some of whom have bodily isomerism. Bodily isomerism or heterotaxy is a unique clinical entity associated with congenital malformations of the heart which further increases the risk for future cardiovascular complications. We aimed to investigate the frequency of arrhythmias in adults with bodily isomerism. We utilized the 2012 iteration of the Nationwide Inpatient Sample to identify adult inpatient admissions associated with arrhythmias in patients with isomerism. Data regarding demographics, comorbidities, and various procedures were collected and compared between those with and without isomerism. A total of 6,907,109 admissions were analyzed with a total of 861 being associated isomerism. The frequency of arrhythmias was greater in those with isomerism (20.8 vs. 15.4 %). Those with isomerism were also more five times more likely to undergo invasive electrophysiology studies. Length and cost of hospitalization for patients with arrhythmias also tended to be greater in those with isomerism. Mortality did not differ between the two groups. Arrhythmias are more prevalent in those with isomerism, with a majority of arrhythmias in isomerism being atrial. Those with isomerism and arrhythmias also tended to have greater length and cost of hospitalization.