Neuroprotective Effect of the Novel Na⁺/Ca²⁺ Channel Blocker NS-7 on Rat Retinal Ganglion Cells

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• 作者：Shinichiro Saito ; Masaaki Ohashi ; Akira Naito ; Yasuhiro Fukaya ; Yasuyuki Suzuki and Makoto Araie
• 关键词：ischemia ; neuroprotection ; NS ; 7 ; rat ; retina
• 刊名：Japanese Journal of Ophthalmology
• 出版年：2005
• 出版时间：September 2005
• 年：2005
• 卷：49
• 期：5
• 页码：371-376
• 全文大小：334 KB

文摘

Purpose To investigate whether NS-7, 4-(4-fluorophenyl)-2-methyl-6-(5-piperidinopentyloxy) pyrimidine hydrochloride, a novel Na+/Ca2+ channel blocker, can protect the rat retina subjected to ischemia–reperfusion insult.