Detection of metallic cobalt and chromium liver deposition following failed hip replacement using T2* and R2 magnetic resonance

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• 作者：Amna Abdel-Gadir ; Reshid Berber…
• 关键词：MRI ; T2* ; Metal ; on ; metal hip ; Cobalt ; Chromium ; Metal loading
• 刊名：Journal of Cardiovascular Magnetic Resonance
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：18
• 期：1
• 全文大小：1,835 KB
• 刊物主题：Imaging / Radiology; Angiology; Cardiology;
• 出版者：BioMed Central
• ISSN：1532-429X
• 卷排序：18

文摘

BackgroundFailed hip prostheses can cause elevated circulating cobalt and chromium levels, with rare reports of fatal systemic organ deposition, including cobalt cardiomyopathy. Although blood cobalt and chromium levels are easily measured, organ deposition is difficult to detect without invasive biopsy. The T2* magnetic resonance (MR) method is used to quantify tissue iron deposition, and plays an important role in the management of iron-loading conditions. Cobalt and chromium, like iron, also affect magnetism and are proposed MR contrast agents.