刊名:Journal of Cancer Research and Clinical Oncology
出版年:2017
出版时间:March 2017
年:2017
卷:143
期:3
页码:551-554
全文大小:
刊物类别:Medicine
刊物主题:Oncology; Cancer Research; Internal Medicine; Hematology;
出版者:Springer Berlin Heidelberg
ISSN:1432-1335
卷排序:143
文摘
PurposeDiffuse-type gastric cancer (DGC) carries a poor prognosis. Effective screening is one measure that might improve the prognosis of this disease. An E-cadherin/p53 double-conditional knockout (DCKO) mouse line recapitulates human DGC morphologically and molecularly. Three circulating microRNAs (miRNA) (miR-103, miR-107, miR-194) in DCKO mice have been identified as biomarkers for DGC. We sought to evaluate whether these circulating miRNAs could be used for the detection of human DGC.
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