Polymyxin B-immobilized fiber column hemoperfusion mainly helps to constrict peripheral blood vessels in treatment for septic shock
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  • 作者:Makiko Sugiura ; Chieko Mitaka ; Go Haraguchi ; Makoto Tomita…
  • 关键词:Severe sepsis ; Septic shock ; Polymyxin B ; Endotoxin ; Hemodynamics ; Hemoperfusion ; Inotropic score
  • 刊名:Journal of Intensive Care
  • 出版年:2015
  • 出版时间:December 2015
  • 年:2015
  • 卷:3
  • 期:1
  • 全文大小:388KB
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  • 作者单位:Makiko Sugiura (1)
    Chieko Mitaka (2)
    Go Haraguchi (3)
    Makoto Tomita (4)
    Naohiko Inase (1)

    1. Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, Japan
    2. Department of Critical Care Medicine, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    3. Division of Intensive Care Unit, New Tokyo Hospital, Chiba, Japan
    4. Medical Clinical Research Center, Tokyo Medical and Dental University, Tokyo, Japan
  • 刊物类别:Intensive / Critical Care Medicine;
  • 刊物主题:Intensive / Critical Care Medicine;
  • 出版者:BioMed Central
  • ISSN:2052-0492
文摘
Background Polymyxin B-immobilized fiber column hemoperfusion (PMX) has been reported to be effective for patients with septic shock. It remains unclear, however, how the efficacy of PMX varies according to the characteristics and underlying conditions of the patients treated. The objective of the present study was to clarify the factors that result in clinical efficacy of PMX treatment.
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