Abnormal sleep patterns in subjects with type II diabetes mellitus and its effect on diabetic microangiopathies: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS, report 20)

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• 作者：Rajiv Raman (1)
  Aditi Gupta (1)
  Kadri Venkatesh (1)
  Vaitheeswaran Kulothungan (2)
  Tarun Sharma (1) drtaruns@gmail.com
• 关键词：Abnormal sleep patterns – Diabetes mellitus – Microangiopathies – Epworth Sleepiness Scale
• 刊名：Acta Diabetologica
• 出版年：2012
• 出版时间：August 2012
• 年：2012
• 卷：49
• 期：4
• 页码：255-261
• 全文大小：207.8 KB
• 参考文献：1. Resnick HE, Redline S, Shahar E, Gilpin A, Newman A, Walter R, Ewy GA, Howard BV, Punjabi NM, Sleep Heart Health Study (2003) Diabetes and sleep disturbances: findings from the Sleep Heart Health Study. Diabetes Care 26(3):702–709
  2. Sridhar GR, Madhu K (1994) Prevalence of sleep disturbances in diabetes mellitus. Diabetes Res Clin Pract 23(3):183–186
  3. Kawakami N, Takatsuka N, Shimizu H (2004) Sleep disturbance and onset of type 2 diabetes. Diabetes Care 27(1):282–283
  4. Gottlieb DJ, Punjabi NM, Newman AB, Resnick HE, Redline S, Baldwin CM, Nieto FJ (2005) Association of sleep time with diabetes mellitus and impaired glucose tolerance. Arch Intern Med 165(8):863–867
  5. Tuomilehto H, Peltonen M, Partinen M, Sepp? J, Saaristo T, Korpi-Hy?v?lti E, Oksa H, Puolijoki H, Saltevo J, Vanhala M, Tuomilehto J (2008) Sleep duration is associated with an increased risk for the prevalence of type 2 diabetes in middle-aged women—The FIN-D2D survey. Sleep Med 9(3):221–227
  6. Chaput JP, Després JP, Bouchard C, Tremblay A (2007) Association of sleep duration with type 2 diabetes and impaired glucose tolerance. Diabetologia 50(11):2298–2304
  7. Ayas NT, White DP, Al-Delaimy WK, Manson JE, Stampfer MJ, Speizer FE, Patel S, Hu FB (2003) A prospective study of self-reported sleep duration and incident diabetes in women. Diabetes Care 26(2):380–384
  8. Mallon L, Broman JE, Hetta J (2005) High incidence of diabetes in men with sleep complaints or short sleep duration: a 12-year follow-up study of a middle-aged population. Diabetes Care 28(11):2762–2767
  9. Yaggi HK, Araujo AB, McKinlay JB (2006) Sleep duration as a risk factor for the development of type 2 diabetes. Diabetes Care 29(3):657–661
  10. Gangwisch JE, Heymsfield SB, Boden-Albala B, Buijs RM, Kreier F, Pickering TG, Rundle AG, Zammit GK, Malaspina D (2007) Sleep duration as a risk factor for diabetes incidence in a large US sample. Sleep 30(12):1667–1673
  11. Zizi F, Jean-Louis G, Brown CD, Ogedegbe G, Boutin-Foster C, McFarlane SI (2010) Sleep duration and the risk of diabetes mellitus: epidemiologic evidence and pathophysiologic insights. Curr Diab Rep 10(1):43–47
  12. Tuomilehto H, Peltonen M, Partinen M, Lavigne G, Eriksson JG, Herder C, Aunola S, Kein?nen-Kiukaanniemi S, Ilanne-Parikka P, Uusitupa M, Tuomilehto J, Lindstr?m J, Finnish Diabetes Prevention Study Group (2009) Sleep duration, lifestyle intervention, and incidence of type 2 diabetes in impaired glucose tolerance: The Finnish Diabetes Prevention Study. Diabetes Care 32(11):1965–1971
  13. Jennum P, Schultz-Larsen K, Christensen N (1993) Snoring, sympathetic activity and cardiovascular risk factors in a 70 year old population. Eur J Epidemiol 9(5):477–482
  14. Grunstein R, Wilcox I, Yang TS, Gould Y, Hedner J (1993) Snoring and sleep apnea in men: association with central obesity and hypertension. Int J Obes Relat Metab Disord 17(9):533–540
  15. Al-Delaimy W, Manson JE, Willett WC, Stampfer MJ, Hu FB (2002) Snoring as a risk factor for type II diabetes mellitus: a prospective study. Am J Epidemiol 155(5):387–393
  16. Elmasry A, Janson C, Lindberg E, Gislason T, Tageldin MA, Boman G (2000) The role of habitual snoring and obesity in the development of diabetes: a 10-year follow-up study in a male population. J Intern Med 248(1):13–20
  17. Renko AK, Hiltunen L, Laakso M, Rajala U, Kein?nen-Kiukaanniemi S (2005) The relationship of glucose tolerance to sleep disorders and daytime sleepiness. Diabetes Res Clin Pract 67(1):84–91
  18. Gislason T, Taube A (1987) Prevalence of sleep apnea syndrome–estimation by two stage sampling. Ups J Med Sci 92(2):193–203
  19. Lindberg E, Berne C, Franklin KA, Svensson M, Janson C (2007) Snoring and daytime sleepiness as risk factors for hypertension and diabetes in women–a population-based study. Respir Med 101(6):1283–1290
  20. Chasens ER, Sereika SM, Burke LE (2009) Daytime sleepiness and functional outcomes in older adults with diabetes. Diabetes Educ 35(3):455–464
  21. Vgontzas AN, Chrousos GP (2002) Sleep-disordered breathing, sleepiness, and insulin resistance: is the latter a consequence, a pathogenetic factor, or both? Sleep Med 3(5):389–391
  22. Knutson KL, Ryden AM, Mander BA, Van Cauter E (2006) Role of sleep duration and quality in the risk and severity of type 2 diabetes mellitus. Arch Intern Med 166(16):1768–1774
  23. Sauvet F, Leftheriotis G, Gomez-Merino D, Langrume C, Drogou C, Van Beers P, Bourrilhon C, Florence G, Chennaoui M (2010) Effect of acute sleep deprivation on vascular function in healthy subjects. J Appl Physiol 108(1):68–75
  24. Bj?rkelund C, Bengtsson C, Lissner L, R?dstr?m K (2002) Women’s sleep: longitudinal changes and secular trends in a 24-year perspective. Results of the population study of women in Gothenburg, Sweden. Sleep 25(8):894–896
  25. Hayashino Y, Fukuhara S, Suzukamo Y, Okamura T, Tanaka T, Ueshima H, HIPOP-OHP Research group (2007) Relation between sleep quality and quantity, quality of life, and risk of developing diabetes in healthy workers in Japan: the High-risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study. BMC Public Health 7:129
  26. Hyypp? MT, Kronholm E (1989) Quality of sleep and chronic illnesses. J Clin Epidemiol 42(7):633–638
  27. Chin K, Oga T, Takahashi K, Takegami M, Nakayama-Ashida Y, Wakamura T, Sumi K, Nakamura T, Horita S, Oka Y, Minami I, Fukuhara S, Kadotani H (2010) Associations between obstructive sleep apnea, metabolic syndrome, and sleep duration, as measured with an actigraph, in an urban male working population in Japan. Sleep 33(1):89–95
  28. Schuster SR, Tabba M, Sahota P (2006) Relationship between the cardiometabolic syndrome and obstructive sleep apnea. J Cardiometab Syndr 1(3):204–208
  29. Chorostowska-Wynimko J, Radomska D, P?ywaczewski R, Jończak L, Stepniewska A, Górecka D, Skopińska-Rózewska E (2005) Disturbed angiogenic activity in sera from obstructive sleep apnea patients. J Physiol Pharmacol 56(Suppl 4):71–77
  30. Agarwal S, Raman R, Paul PG, Rani PK, Uthra S, Gayathree R, McCarty C, Kumaramanickavel G, Sharma T (2005) Sankara Nethralaya-Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS 1): study design and research methodology. Ophthalmic Epidemiol 12(2):143–153
  31. Touitou Y, Portaluppi F, Smolensky MH, Rensing L (2004) Ethical principles and standards for the conduct of human and animal biological rhythm research. Chronobiol Int 21(1):161–170
  32. American Diabetes Association (2003) Tests of glycemia in diabetes. Diabetes Care 26(Suppl 1):s106–s108
  33. Klein R, Klein BE, Magli YL, Brothers RJ, Meuer SM, Moss SE, Davis MD (1986) An alternative method of grading diabetic retinopathy. Ophthalmology 93(9):1183–1187
  34. Molitch ME, DeFronzo RA, Franz MJ, Keane WF, Mogensen CE, Parving HH, Steffes MW, American Diabetes Association (2004) Nephropathy in diabetes. Diabetes Care 27(Suppl 1):S79–S83
  35. Pradeepa R, Rema M, Vignesh J, Deepa M, Deepa R, Mohan V (2008) Prevalence and risk factors for diabetic neuropathy in an urban south Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55). Diabet Med 25(4):407–412
  36. Nevsimalova S (2002) Excessive daytime sleepiness. In: Reisin RC, Nuwer MR, Hallett M, Medina C (eds) Advances in clinical neurophysiology: supplements to clinical neurophysiology, 1st edn. Elsevier, The Netherlands, pp 175–179
  37. Johns MW (1993) Daytime sleepiness, snoring, and obstructive sleep apnea. The Epworth sleepiness Scale. Chest 103(1):30–36
  38. Spiegel K, Tasali E, Penev P, Van Cauter E (2004) Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med 141(11):846–850
  39. Meisinger C, Heier M, Loewel H, MONICA/KORA Augsburg Cohort study (2005) Sleep disturbance as a predictor of type 2 diabetes mellitus in men and women from the general population. Diabetologia 48(2):235–241
  40. Spiegel K, Leproult R, Van Cauter E (1999) Impact of sleep debt on metabolic and endocrine function. Lancet 354(9188):1435–1439
  41. Wolk R, Svatikova A, Nelson CA, Gami AS, Govender K, Winnicki M, Somers VK (2005) Plasma levels of adiponectin, a novel adipocyte-derived hormone, in sleep apnea. Obes Res 13(1):186–190
  42. Raman R, Rani PK, Gnanamoorthy P, Sudhir RR, Kumaramanikavel G, Sharma T (2010) Association of obesity with diabetic retinopathy: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study (SN-DREAMS Report no. 8). Acta Diabetol 47(3):209–215
• 作者单位：1. Shri Bhagwan Mahavir Vitreoretinal Services, 18, College Road, Sankara Nethralaya, Chennai, 600 006 Tamil Nadu, India2. Department of Preventive Ophthalmology (Epidemiology and Biostatistics), 18, College Road, Sankara Nethralaya, Chennai, 600 006 Tamil Nadu, India
• ISSN：1432-5233

文摘

To study the prevalence of Abnormal Sleep Patterns (ASPs), gender-wise, in subjects with type II diabetes mellitus and its influence on diabetic microangiopathies. A population-based cross-sectional survey was conducted among 1,414 patients having type II diabetes mellitus. Diabetic retinopathy was graded using stereoscopic digital fundus photography. Neuropathy was assessed by measuring vibration perception threshold using a sensitometer. Nephropathy was diagnosed by the presence of microalbuminuria in the first morning urine sample. ASPs were defined as either short (less than 5 h) or long (more than 9 h) duration of sleep with excessive daytime sleepiness. The Epworth Sleepiness Scale (ESS) score was assessed to note excessive daytime sleepiness; a score of more than 10 was considered as abnormal. The prevalence of ASPs was more in subjects with diabetes than with those without diabetes (14.8 vs. 6.6%) (P = 0.009), especially in women (15.7 vs. 5.6%) (P = 0.021). Likewise, the prevalence of short duration of sleep was higher in subjects with diabetes compared to those without diabetes (6.6 vs. 2.2%) (P = 0.040). The mean age of women subjects with diabetes, having ASPs, was higher than those without diabetes (56.4 ± 8.9 years vs. 47.2 ± 5.9 years, P = 0.033). Women subjects with ASPs had a higher risk of diabetic neuropathy on both univariate and multivariate analysis. ASPs are not only related to diabetes but can also influence the microvascular complications arising due to diabetes, particularly diabetic neuropathy. Diabetology and sleep medicine specialists need to work together to prevent the negative interactions between these two groups.