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- 作者:PD Dr. O. Drognitz (1)
H. Neeff (1) U.T. Hopt (1) P. Pisarski (1)
- 关键词:Isolierte Pankreastransplantation ; Pankreas ; nach Nierentransplantation ; Simultane Pankreas ; Nieren ; Transplantation ; Blutzuckerkontrolle ; Lebensqualit?t ; Pancreas transplant alone ; Pancreas after kidney transplant ; Simultaneous pancreas ; kidney transplant ; Glucose control ; Quality of life
- 刊名:Der Gastroenterologe
- 出版年:2009
- 出版时间:November 2009
- 年:2009
- 卷:4
- 期:6
- 页码:540-547
- 全文大小:576KB
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2. The Diabetes Control and Complications Trial Research Group (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329: 977-86 CrossRef 3. Shapiro AM, Ricordi C, Hering BJ et al (2006) International trial of the Edmonton protocol for islet transplantation. N Engl J Med 355: 1318-330 CrossRef 4. Ryan EA, Paty BW, Senior PA et al (2005) Five-year follow-up after clinical islet transplantation. Diabetes 54: 2060-069 CrossRef 5. American Diabetes Association (1992) Pancreas transplantation for patients with diabetes mellitus. Diabetes care 15: 1668-672 6. White SA, Shaw JA, Sutherland DE (2009) Pancreas transplantation. Lancet 373: 1808-817 CrossRef 7. Scalea JR, Butler CC, Munivenkatappa RB et al (2008) Pancreas transplant alone as an independent risk factor for the development of renal failure: a retrospective study. Transplantation 86: 1789-794 CrossRef 8. 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Clin Transplant 19: 433-55 CrossRef 18. Gaber AO, Shokouh-Amiri H, Grewal HP, Britt LG (1993) A technique for portal pancreatic transplantation with enteric drainage. Surg Gynecol Obstet 177: 417-19 19. Pfeffer F, Nauck MA, Erb M et al (1997) Absence of severe hyperinsulinemia after pancreas/kidney transplantation with peripheral venous drainage. Transplant Proc 29: 645-46 CrossRef 20. Fontbonne A, Charles MA, Thibult N et al (1991) Hyperinsulinaemia as a predictor of coronary heart disease mortality in a healthy population: the Paris Prospective Study, 15-year follow-up. Diabetologia 34: 356-61 CrossRef 21. Hummel R, Langer M, Wolters HH et al (2008) Exocrine drainage into the duodenum: a novel technique for pancreas transplantation. Transpl Int 21: 178-81 22. Saudek F, Malaise J, Boucek P, Adamec M (2005) Efficacy and safety of tacrolimus compared with cyclosporin microemulsion in primary SPK transplantation: 3-year results of the Euro-SPK 001 trial. Nephrol Dial Transplant 20(Suppl 2): ii3–ii10, ii62 CrossRef 23. Stratta RJ, Gaber AO, Shokouh-Amiri MH et al (1999) Evolution in pancreas transplantation techniques: simultaneous kidney-pancreas transplantation using portal-enteric drainage without antilymphocyte induction. Ann Surg 229: 701-08 CrossRef 24. Malaise J, Nakache R, Kahl A et al (2005) Corticosteroid withdrawal in simultaneous pancreas-kidney transplantation: a 3-year report. Transplant Proc 37: 2853-855 CrossRef 25. Cantarovich D, Vistoli F (2009) Minimization protocols in pancreas transplantation. Transpl Int 22: 61-8 CrossRef 26. Fernandez-Cruz L, Sabater L, Gilabert R et al (1993) Native and graft pancreatitis following combined pancreas-renal transplantation. Br J Surg 80: 1429-432 CrossRef 27. Benz S, Bergt S, Obermaier R et al (2001) Impairment of microcirculation in the early reperfusion period predicts the degree of graft pancreatitis in clinical pancreas transplantation. Transplantation 71: 759-63 CrossRef 28. 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Tyden G, Bolinder J, Solders G et al (1999) Improved survival in patients with insulin-dependent diabetes mellitus and end-stage diabetic nephropathy 10 years after combined pancreas and kidney transplantation. Transplantation 67: 645-48 CrossRef 34. Ojo AO, Meier-Kriesche HU, Hanson JA et al (2001) The impact of simultaneous pancreas-kidney transplantation on long-term patient survival. Transplantation 71: 82-0 CrossRef 35. Pruijm MT, de Fijter HJ, Doxiadis II, Vandenbroucke JP (2006) Preemptive versus Non-preemptive simultaneous pancreas-kidney transplantation: a single-center, long-term, follow-up study. Transplantation 81: 1119-124 CrossRef 36. Ablorsu E, Ghazanfar A, Mehra S et al (2008) Outcome of pancreas transplantation in recipients older than 50 years: a single-centre experience. Transplantation 86: 1511-514 CrossRef 37. Weiss AS, Smits G, Wiseman AC (2009) Simultaneous pancreas-kidney versus deceased donor kidney transplant: can a fair comparison be made? Transplantation 87: 1402-410 CrossRef 38. Secchi A, Caldara R, La RE et al (1998) Cardiovascular disease and neoplasms after pancreas transplantation. Lancet 352: 65 CrossRef 39. Venstrom JM, McBride MA, Rother KI et al (2003) Survival after pancreas transplantation in patients with diabetes and preserved kidney function. JAMA 290: 2817-823 CrossRef 40. Gruessner RW, Sutherland DE, Gruessner AC (2004) Mortality assessment for pancreas transplants. Am J Transplant 4: 2018-026 CrossRef 41. Hopt UT, Drognitz O (2000) Pancreas organ transplantation. Short and long-term results in terms of diabetes control. Langenbecks Arch Surg 385: 379-89 CrossRef 42. Piehlmeier W, Bullinger M, Kirchberger I et al (1996) Evaluation of the quality of life of patients with insulin-dependent diabetes mellitus before and after organ transplantation with the SF 36 health survey. Eur J Surg 162: 933-40
- 作者单位:PD Dr. O. Drognitz (1)
H. Neeff (1) U.T. Hopt (1) P. Pisarski (1)
1. Abt. Allgemein- und Viszeralchirurgie, Klinik und Poliklinik für Chirurgie, Universit?tsklinikum Freiburg, Hugstetter Str. 55, 79106, Freiburg im Breisgau, Deutschland
文摘
Pancreas transplantation is an effective and highly successful procedure for restoring physiological glucose control in diabetics. In contrast to islet transplantation, long-term results beyond 5?years can be achieved for the majority of patients. Simultaneous pancreas and kidney transplantation is the therapy of choice for type?1 diabetics with end-stage renal failure. This procedure leads to a threefold longer life expectancy compared with patients on the waiting list. These results are mainly due to a decreased mortality rate from cardiovascular events. This article reviews the indications, timing, surgical technique, complications, and results of pancreas transplantation.
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