miR-27b inhibits fibroblast activation via targeting TGFβ signaling pathway

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• 作者：Xiangming Zeng ; Chaoqun Huang ; Lakmini Senavirathna ; Pengcheng Wang…
• 关键词：miR ; 27b ; Fibroblast activation ; TGFβ ; Idiopathic pulmonary fibrosis
• 刊名：BMC Cell Biology
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：18
• 期：1
• 全文大小：833KB
• 刊物主题：Cell Biology; Biological Microscopy; Life Sciences, general;
• 出版者：BioMed Central
• ISSN：1471-2121
• 卷排序：18

文摘

BackgroundMicroRNAs are a group of small RNAs that regulate gene expression at the posttranscriptional level. They regulate almost every aspect of cellular processes. In this study, we investigated whether miR-27b regulates pulmonary fibroblast activation.