Hautalterung und evidenzbasierte topische Anti-Aging-Strategien

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• 作者：Prof. Dr. C. Bayerl
• 关键词：Dermatologie ; Prävention ; Hautalterung ; Sonnenschutz ; Vitamin ; A ; Säure ; Derivate ; Dermatology ; Prevention ; Skin aging ; Sun screens ; Retinoic acid derivatives
• 刊名：Der Hautarzt
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：67
• 期：2
• 页码：140-147
• 全文大小：365 KB
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• 作者单位：Prof. Dr. C. Bayerl (1)
  
  1. Klinik für Dermatologie und Allergologie, Hauttumorzentrum Wiesbaden, Helios Dr. Horst Schmidt Kliniken, Ludwig-Erhard-Straße 100, 65199, Wiesbaden, Deutschland
  
• 刊物主题：Dermatology; Immunology; Allergology; Proctology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-1173

文摘

Anti-aging in dermatology primarily focuses on the prevention of skin aging with UV protection (clothing and sunsceens), free radical scavengers (synthetic or botanic), and cell-protecting agents such as vitamin B₃. For the correction of signs of early skin aging, retinoic acid derivatives in dermatological prescriptions are the best studied substances. Topical hormonal prescriptions are also an option if UV damage has not been the leading culprit for aging. Chemical peeling leads to a marked increase in collagen formation, the deaper the better. Ingredients in cream preparations can reduce superficial skin folds (polyphenols, amino acid peptides). Modulators of regular pigmentation are important for anti-aging preparations. Growth factors (plant extracts, recombinant growth factors) are not thoroughly studied regarding the cost–benefit and risk ratio. Complex precedures such as photodynamic therapy have an impact on the appearance of aged skin. Keywords Dermatology Prevention Skin aging Sun screens Retinoic acid derivatives