Experimental validation of contrast-enhanced SSFP cine CMR for quantification of myocardium at risk in acute myocardial infarction

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• 作者：David Nordlund ; Mikael Kanski…
• 关键词：Myocardium at risk ; CE ; SSFP ; AAR ; Area at risk
• 刊名：Journal of Cardiovascular Magnetic Resonance
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：19
• 期：1
• 全文大小：2513KB
• 刊物主题：Imaging / Radiology; Angiology; Cardiology;
• 出版者：BioMed Central
• ISSN：1532-429X
• 卷排序：19

文摘

BackgroundAccurate assessment of myocardium at risk (MaR) after acute myocardial infarction (AMI) is necessary when assessing myocardial salvage. Contrast-enhanced steady-state free precession (CE-SSFP) is a recently developed cardiovascular magnetic resonance (CMR) method for assessment of MaR up to 1 week after AMI. Our aim was to validate CE-SSFP for determination of MaR in an experimental porcine model using myocardial perfusion single-photon emission computed tomography (MPS) as a reference standard and to test the stability of MaR-quantification over time after injecting gadolinium-based contrast.