Stereoselective biotransformation of racemic mandelic acid using immobilized laccase and (S)-mandelate dehydrogenase

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• 作者：Xing Chen ; Chengli Yang ; Peng Wang ; Xuan Zhang…
• 关键词：Biocatalysis ; (S) ; Mandelate dehydrogenase ; Laccase ; Immobilization ; Chitosan ; Bi ; enzymatic system
• 刊名：Bioresources and Bioprocessing
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：4
• 期：1
• 全文大小：1641KB
• 刊物类别：Biochemical Engineering; Environmental Engineering/Biotechnology; Industrial and Production Engineer
• 刊物主题：Biochemical Engineering; Environmental Engineering/Biotechnology; Industrial and Production Engineering;
• 出版者：Springer Berlin Heidelberg
• ISSN：2197-4365
• 卷排序：4

文摘

Objectives(S)-Mandelate dehydrogenase (SMDH) and laccase were immobilized on chitosan. The bi-enzymatic system with immobilized SMDH and immobilized laccase was taken to catalyze the stereoselective transformation of racemic mandelic acid and (R)-mandelic acid was obtained from its racemic mixture.