False positive diagnosis on ¹³¹iodine whole-body scintigraphy of differentiated thyroid cancers

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• 作者：Vincenzo Triggiani ; Vito Angelo Giagulli ; Michele Iovino ; Giovanni De Pergola…
• 关键词：Thyroid scintigraphy ; Whole ; body scintigraphy ; Differentiated thyroid cancer ; 131Iodine ; Natrium/iodide symporter ; Radioiodine uptake ; Metastatic thyroid cancer
• 刊名：Endocrine
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：53
• 期：3
• 页码：626-635
• 全文大小：5,530 KB
• 刊物主题：Endocrinology; Diabetes; Internal Medicine; Science, general;
• 出版者：Springer US
• ISSN：1559-0100
• 卷排序：53

文摘

131Iodine is used both to ablate any residual thyroid tissue or metastatic disease and to obtain whole-body diagnostic images after total thyroidectomy for differentiated thyroid cancer (DTC). Even though whole-body scan is highly accurate in showing thyroid residues as well as metastases of DTC, false positive results can be found, possibly leading to diagnostic errors and unnecessary treatments. This paper reviews the physiological and pathological processes involved as well as the strategy to recognize and rule out false positive radioiodine images.