Association between the -159C/T polymorphism in the promoter region of the CD14 gene and sepsis: a meta-analysis

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• 作者：Qin Wu ; Xiaomeng Xu ; Jianan Ren ; Song Liu ; Xuelian Liao ; Xiuwen Wu…
• 关键词：CD14 ; 159C/T ; Polymorphism ; rs2569190 ; Sepsis ; Susceptibility ; Mortality
• 刊名：BMC Anesthesiology
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：1001KB
• 刊物主题：Anesthesiology; Internal Medicine; Emergency Medicine; Intensive / Critical Care Medicine;
• 出版者：BioMed Central
• ISSN：1471-2253
• 卷排序：17

文摘

BackgroundThe association between CD14-159C/T polymorphism and sepsis has been assessed but results of current studies appeared conflicting and inconstant. This analysis was aimed to determine whether the CD14-159C/T polymorphism confers susceptibility to sepsis or is associated with increased risk of death from sepsis.