Fluids and sepsis: changing the paradigm of fluid therapy: a case report

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• 作者：Hori Hariyanto ; Corry Quando Yahya ; Monika Widiastuti…
• 关键词：Sepsis ; Septic shock ; Fluid management ; Fluid overload ; Geriatric ; Case report
• 刊名：Journal of Medical Case Reports
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：11
• 期：1
• 全文大小：1430KB
• 刊物主题：Medicine/Public Health, general; General Practice / Family Medicine; Public Health; Primary Care Medicine;
• 出版者：BioMed Central
• ISSN：1752-1947
• 卷排序：11

文摘

BackgroundOver the past 16 years, sepsis management has been guided by large-volume fluid administration to achieve certain hemodynamic optimization as advocated in the Rivers protocol. However, the safety of such practice has been questioned because large-volume fluid administration is associated with fluid overload and carries the worst outcome in patients with sepsis. Researchers in multiple studies have declared that using less fluid leads to increased survival, but they did not describe how to administer fluids in a timely and appropriate manner.