Whole genome sequencing reveals high-resolution epidemiological links between clinical and environmental Klebsiella pneumoniae

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• 作者：Chakkaphan Runcharoen ; Danesh Moradigaravand ; Beth Blane…
• 关键词：Klebsiella pneumoniae ; Whole genome sequencing ; Antibiotic resistance ; Genomic epidemiology
• 刊名：Genome Medicine
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：9
• 期：1
• 全文大小：1067KB
• 刊物主题：Human Genetics; Metabolomics; Bioinformatics; Medicine/Public Health, general; Cancer Research; Systems Biology;
• 出版者：BioMed Central
• ISSN：1756-994X
• 卷排序：9

文摘

BackgroundKlebsiella pneumoniae is a gram-negative bacterial species capable of occupying a broad range of environmental and clinical habitats. Known as an opportunistic pathogen, it has recently become a major causative agent of clinical infections worldwide. Despite growing knowledge about the highly diverse population of K. pneumoniae, the evolution and clinical significance of environmental K. pneumoniae, as well as the relationship between clinical and environmental K. pneumoniae, are poorly defined.