Automatic segmentation of myocardium at risk from contrast enhanced SSFP CMR: validation against expert readers and SPECT

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• 作者：Jane Tufvesson ; Marcus Carlsson ; Anthony H. Aletras ; Henrik Engblom…
• 关键词：Quantification ; Myocardial salvage ; Randomized clinical trials ; Expectation maximization ; A priori information ; Surface coil correction
• 刊名：BMC Medical Imaging
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：16
• 期：1
• 全文大小：2,560 KB
• 刊物主题：Imaging / Radiology;
• 出版者：BioMed Central
• ISSN：1471-2342

文摘

Background Efficacy of reperfusion therapy can be assessed as myocardial salvage index (MSI) by determining the size of myocardium at risk (MaR) and myocardial infarction (MI), (MSI = 1-MI/MaR). Cardiovascular magnetic resonance (CMR) can be used to assess MI by late gadolinium enhancement (LGE) and MaR by either T2-weighted imaging or contrast enhanced SSFP (CE-SSFP). Automatic segmentation algorithms have been developed and validated for MI by LGE as well as for MaR by T2-weighted imaging. There are, however, no algorithms available for CE-SSFP. Therefore, the aim of this study was to develop and validate automatic segmentation of MaR in CE-SSFP.