Use of the cysteine-repressible HpMET3 promoter as a novel tool to regulate gene expression in Hansenula polymorpha

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• 作者：Su Jin Yoo ; Seung Yeon Chung ; Dong-jik Lee ; Hyunah Kim…
• 关键词：ATP sulfurylase ; Cysteine ; Hansenula polymorpha ; O ; Mannosyltransferase ; MET3 ; Promoter ; Regulation
• 刊名：Biotechnology Letters
• 出版年：2015
• 出版时间：November 2015
• 年：2015
• 卷：37
• 期：11
• 页码：2237-2245
• 全文大小：1,133 KB
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• 作者单位：Su Jin Yoo (1)
  Seung Yeon Chung (1)
  Dong-jik Lee (1)
  Hyunah Kim (1)
  Seon Ah Cheon (1)
  Hyun Ah Kang (1)
  
  1. Department of Life Science, College of Natural Science, Chung-Ang University, Seoul, 156-756, Korea
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Microbiology
  Biotechnology
  Applied Microbiology
  Biochemistry
  
• 出版者：Springer Netherlands
• ISSN：1573-6776

文摘

Objectives The promoter of HpMET3, encoding an ATP sulfurylase, was evaluated for its potential as a repressible promoter to downregulate the expression of target genes in the thermotolerant, methylotrophic yeast Hansenula polymorpha.