A phase I and pharmacokinetic study of ganetespib (STA-9090) in advanced hepatocellular carcinoma
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  • 作者:Lipika Goyal (1) (3)
    Raymond C. Wadlow (4)
    Lawrence S. Blaszkowsky (1) (3)
    Brian M. Wolpin (2) (3)
    Thomas A. Abrams (2) (3)
    Nadine Jackson McCleary (2) (3)
    Susan Sheehan (1)
    Eamala Sundaram (1)
    Michael D. Karol (5)
    John Chen (5)
    Andrew X. Zhu (1) (3)
  • 关键词:Hepatocellular carcinoma ; STA ; 9090 ; Ganetespib ; Phase I ; Heat shock protein inhibitors ; Pharmacokinetics ; Hepatic dysfunction
  • 刊名:Investigational New Drugs
  • 出版年:2015
  • 出版时间:February 2015
  • 年:2015
  • 卷:33
  • 期:1
  • 页码:128-137
  • 全文大小:278 KB
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  • 作者单位:Lipika Goyal (1) (3)
    Raymond C. Wadlow (4)
    Lawrence S. Blaszkowsky (1) (3)
    Brian M. Wolpin (2) (3)
    Thomas A. Abrams (2) (3)
    Nadine Jackson McCleary (2) (3)
    Susan Sheehan (1)
    Eamala Sundaram (1)
    Michael D. Karol (5)
    John Chen (5)
    Andrew X. Zhu (1) (3)

    1. Massachusetts General Hospital Cancer Center, 55 Fruit Street, LH/PB 220, Boston, MA, 02114, USA
    3. Harvard Medical School, Boston, MA, USA
    4. Virginia Cancer Specialists, Fairfax, VA, USA
    2. Dana Farber Cancer Institute, Boston, MA, USA
    5. Synta Pharmaceuticals Corp, Lexington, MA, USA
  • 刊物类别:Medicine
  • 刊物主题:Medicine & Public Health
    Oncology
    Pharmacology and Toxicology
  • 出版者:Springer Netherlands
  • ISSN:1573-0646
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